The second volume in the CURRENT TOPICS IN NONCLINICAL DRUG
DEVELOPMENT SERIES explores the critical issues and current topics
in nonclinical drug development. This second volume covers
individual topics and strategies in drug development from compound
characterization to drug registration. Written by a variety of
experts in the field, recent and rapid advances in technologies and
associated changes in regulatory guidance are discussed. Select
topics include: Evolution of Artificial Intelligence (AI)
technologies and the impact on toxicologic pathology. Current
approaches to carcinogenicity testing. Predicting drug-drug
interactions Current understanding of idiosyncratic drug reaction.
Assessing cardiovascular risks beyond QT interval. Use of 3-D cell
cultures in toxicology and ADME. Development of small
molecule-antibody complexes. Differentiating adverse from
non-adverse finding is nonclinical studies. Current Topics in
Nonclinical Drug Development: Volume 2 will aid toxicologists,
toxicologic pathologists, consultants, regulators, Study Directors,
and nonclinical scientists dealing with day-to-day issues
encountered in drug development and assist in formulating
strategies for resolution of these issues. In addition, the book
will be a valuable reference for academicians and graduate students
pursuing research related to nonclinical drug development.
General
| Imprint: |
Crc Press
|
| Country of origin: |
United Kingdom |
| Series: |
Current Topics in Nonclinical Drug Development Series |
| Release date: |
October 2023 |
| First published: |
2024 |
| Editors: |
Philip Bentley
• Pritam S. Sahota
• Zbigniew Wojcinski
|
| Dimensions: |
234 x 156mm (L x W) |
| Pages: |
528 |
| ISBN-13: |
978-0-367-46668-8 |
| Categories: |
Books
|
| LSN: |
0-367-46668-6 |
| Barcode: |
9780367466688 |
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