The Quasispecies Equation and Classical Population Models (1st ed. 2022)

This monograph studies a series of mathematical models of the evolution of a population under mutation and selection. Its starting point is the quasispecies equation, a general non-linear equation which describes the mutation-selection equilibrium in Manfred Eigen’s famous quasispecies model. A detailed analysis of this equation is given under the assumptions of finite genotype space, sharp peak landscape, and class-dependent fitness landscapes. Different probabilistic representation formulae are derived for its solution, involving classical combinatorial quantities like Stirling and Euler numbers. It is shown how quasispecies and error threshold phenomena emerge in finite population models, and full mathematical proofs are provided in the case of the Wright–Fisher model. Along the way, exact formulas are obtained for the quasispecies distribution in the long chain regime, on the sharp peak landscape and on class-dependent fitness landscapes. Finally, several other classical population models are analyzed, with a focus on their dynamical behavior and their links to the quasispecies equation.  This book will be of interest to mathematicians and theoretical ecologists/biologists working with finite population models.  

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Probability Theory and Stochastic Modelling, 102
Release date:	August 2023
First published:	2022
Authors:	Raphaël Cerf • Joseba Dalmau
Dimensions:	235 x 155mm (L x W)
Pages:	242
Edition:	1st ed. 2022
ISBN-13:	978-3-03-108665-6
Categories:	Books Promotions
LSN:	3-03-108665-1
Barcode:	9783031086656

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