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Biofilm Associated on Antimicrobial Resistance and Its Recovery
Loot Price: R3,687
Discovery Miles 36 870
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Biofilm Associated on Antimicrobial Resistance and Its Recovery
Expected to ship within 12 - 17 working days
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A biofilm is a collection of microbial cells that have adhered to
biotic surfaces such as plant cuticles or animal epithelia, as well
as abiotic surfaces such as rocky substratum or catheter exteriors.
The life cycle of microorganism includes the fundamental process of
biofilm formation for survival in diverse and harsh environments
since it is a protected mode of growth allowing colonisation of new
habitats by dispersal of microbes from the microbial clusters. The
biofilm bound microorganisms remain embedded in an extracellular
polymeric matrix that protects the indwelling cells from
surfactants, biocides, several invaders like protozoans, and
defences offered by the hosts like phagocytic cells. The biofilm
bound recalcitrant microbes induce chronic and nosocomial diseases,
posing a serious threat to public health. It has been observed that
various antimicrobial drugs are able to successfully remove the
planktonic (freely suspended) states of microbes as compared to the
sessile (substrate-bound) forms, thus resulting in the development
of antimicrobial resistance. Modern pharmacological strategies
targeting the biofilm matrix differ from the conventional methods
of antibiotic usage. This includes the use of natural compounds
such as plant bioactive molecules, antimicrobial peptides, green
synthesised nanoparticles, or secondary metabolites from other
organisms that not only prevent the rise of antimicrobial
resistance but are also safe for the host tissues. The book titled
"Biofilm Associated on Antimicrobial Resistance and Its Recovery"
provides a detailed and systematic review of alternative
pharmacological developments in the field of biofilm research.
Features: A narrative overview of the mechanism of biofilm
formation and its role in the emergence of antimicrobial
resistance. Recent research in the development of antibiofilm
remedies involving biogenic compounds. Advancements in the biofilm
detection methodologies with the cutting-edge technologies. This
book serves as a reference book for researchers who need to
understand and analyze the progression of events during microbial
biofilm formation, as well as design safer methodologies for its
successful eradication. It may also be used as a textbook for a
graduate level course in microbiology or microbial biotechnology.
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