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Books > Medicine > Surgery > Orthopaedics & fractures
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Vanishing Bone - Conquering a Stealth Disease Caused by Total Hip Replacements (Hardcover)
Loot Price: R748
Discovery Miles 7 480
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Vanishing Bone - Conquering a Stealth Disease Caused by Total Hip Replacements (Hardcover)
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When dozens of holes appeared in a patient's femur alongside his
hip prosthesis, experts were baffled as such a phenomenon had never
been seen before. Over the first four decades of total hip surgery,
the severe bone destruction multiplied, crippling many thousands of
patients. Eventually identified as "periprosthetic osteolysis,"
this devastating disease affected over 1 million patients and was
the leading cause of failure in total hip surgery. While total hip
surgery dramatically reversed severe arthritis of the hip, the same
operation simultaneously created a relentless 'particle generator'
in the body. Ironically, in the effort to do good, doctors were
simultaneously doing major harm. Vanishing Bone: Conquering a
Stealth Disease Caused by Total Hip Replacements takes readers on a
detective adventure in contemporary medical science, from the
identification of the cause of the disease through the complex
process of affecting its cure. Dr. William H. Harris and his
colleagues played an important role in solving the mystery of this
disease, pointing to its molecular biology, recognizing the unusual
wear of the prostheses, and ultimately developing a new material
for use in the manufacture of hip implants. With more than 6
million people walking on this stable, low-wear material, the
disease has been virtually eliminated among those with total hip
replacements worldwide. Diseases are rarely observed, revealed, and
eliminated in one lifetime. Vanishing Bone tells the captivating
story of one such disease through an engaging account of scientific
and medical innovation.
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