PRECALCULUS: MATHEMATICS FOR CALCULUS, 8th INTERNATIONAL METRIC EDITION prepares students to succeed in future calculus courses.

This best-selling author team emphasizes problem-solving and mathematical modeling as this edition presents concepts with unparalleled clarity and precision. Updated content and revised learning features remove barriers for a carefully planned, inclusive learning experience.

The authors' attention to detail and clarity makes this resource a proven market leader.

Sleep Loss and Obesity: Intersecting Epidemics represents a major contribution to the field of sleep medicine. It is a comprehensive review of the neurobiology of sleep, circadian timing and obesity, the deleterious effects of sleep loss and obesity on health, and the worrisome associated social and medical costs in a range of patient populations and overall to society. The number of individuals who are obese has reached alarming levels. As a result, the incidence of Type 2 diabetes, cardiovascular disorders, heart disease, and kidney failure have also increased. The surgeon general estimates that the total annual cost of obesity in the US is about $117 billion. This cost is expected to escalate significantly because the number of overweight and obese children is increasing rapidly. Indeed, the new generation is expected to have a shorter life-span then their parents. In addition, sleep loss is emerging as an important contributing factor to obesity. People who sleep less or are sleep deprived tend to eat more, especially carbohydrates, and have a higher body mass index. Increased weight restricts the upper airway, causing obstructive sleep apnea and further sleep loss. In the end there is a vicious cycle of weight gain and sleep loss. In the past few years there has been a tremendous growth in our understanding of brain mechanisms controlling energy metabolism. Interestingly the neurons regulating waking also regulate feeding. There is also a mechanism that regulates the timing of feeding and sleep. In shift-workers this system is likely to be disturbed, and this has an adverse impact on both feeding and sleep. Sleep Loss and Obesity: Intersecting Epidemics is the first title to clearly examine how obesity and sleep loss are interacting epidemics. This fascinating title makes the link between energy metabolism, sleep and circadian timing; identifies poor sleep as a risk-factor for obesity in children and adults and offers treatment strategies for obstructive sleep apnea and obesity. This book will be a vital source of information for all physicians interested in sleep disorders and obesity. It will also be of value to neuroscientists, health system administrators, and policy makers.

Sleep has recently been recognized as a critical determinant of energy balance regulating, restoration and repair of many of the physiologic and psychologic processes involved in modulating energy intake and utilization. In addition to having an impact on obesity, sleep abnormalities, both quantitative and qualitative, have now been shown to have significant effects on obesity associated comorbidities, including metabolic syndrome, premalignant lesions and cancer. Sleep problems and fatigue also constitute a significant challenge for the ever expanding group of cancer survivors. Moreover, circadian misalignment, such as that experienced by "shift workers" has been shown to be associated with an increased incidence of several malignancies including, breast, colorectal and prostate cancer, consistent with the increasing recognition of the role of clock genes in the metabolic processes. Of increasing concern is the accelerating incidence of sleep disorders in childhood, their association with childhood obesity and associated abnormalities of circulating cytokines, adipokines and metabolic factors, many of which are implicated as etiologic mediators of the connection between obesity and cancer. Extensive studies have now been initiated to investigate the mechanisms by which disturbances in sleep duration, sleep continuity and sleep related breathing affect circadian rhythm, central and peripheral tissue oxygenation and metabolism, quality and quantity of dietary intake and circulating inflammatory cytokines and regulatory hormones. This volume aims to present the latest research on sleep, sleep disturbance and its correlation to obesity and cancer.

Gain a solid foundation in the principles of mathematical thinking with the algebra and trigonometry textbook that's written so you can understand it. ALGEBRA AND TRIGONOMETRY, 5th Edition by best-selling author team Stewart/Redlin/Watson explains concepts simply and clearly, helping you grasp the math that you need to succeed in this course. This edition provides updated guidelines on how to solve problems for each topic. New, helpful review and revised practice opportunities work with new content as the authors introduce problem solving and mathematical modeling early in the book and emphasize these principles throughout. Comprehensive and evenly paced, this edition introduces the function concept and guides you in using a graphing calculator as you develop insights into mathematical ideas. Online WebAssign resources are also available to provide interactive practice and assist you in mastering key principles.

AN ESSENTIAL NEW RESOURCE ON A FUNDAMENTAL DETERMINANT OF HEALTH Sleep, along with the sleep-related behaviors that impact sleep quality, have emerged as significant determinants of health and well-being across populations. An emerging body of research has confirmed that sleep is strongly socially patterned, following trends along lines of socioeconomic status, race, immigration status, age, work, and geography. The Social Epidemiology of Sleep serves as both an introduction to sleep epidemiology and a synthesis of the most important and exciting research to date, including: * An introduction to sleep epidemiology, including methods of assessment and their validity, the descriptive epidemiology of sleep patterns and disorders, associations with health, and basic biology * What we know about the variation of sleep patterns and disorders across populations, including consideration of sleep across the lifespan and within special populations * Major social determinants of sleep (including socioeconomic status, immigration status, neighborhood contexts, and others) based on the accumulated research With editors from both population science and medicine, combined with contributions from psychology, sociology, demography, geography, social epidemiology, and medicine, this text codifies a new field at the intersection of how we sleep and the social and behavioral factors that influence it.

Do you find yourself attempting to memorize facts and mimicking examples simply to make it through algebra? Learn to think mathematically and develop genuine problem-solving skills with COLLEGE ALGEBRA, 8th Edition by best-selling author team Stewart/Redlin/Watson. This straightforward, easy-to-use book helps you master the fundamentals of algebra with updated learning features and new tools for success. New concept exercises at the beginning of each exercise set guide you step-by-step through the main topics of a section. Lists of formulas and key concepts after each chapter reinforce what you've learned, while new review material helps you gauge your progress. In addition, numerous examples show you how to use mathematics to model real situations in fields like engineering, business, physics, chemistry and biology. Online WebAssign resources are also available to provide interactive practice and strengthen your understanding of key principles.

Sleep has recently been recognized as a critical determinant of energy balance regulating, restoration and repair of many of the physiologic and psychologic processes involved in modulating energy intake and utilization. In addition to having an impact on obesity, sleep abnormalities, both quantitative and qualitative, have now been shown to have significant effects on obesity associated comorbidities, including metabolic syndrome, premalignant lesions and cancer. Sleep problems and fatigue also constitute a significant challenge for the ever expanding group of cancer survivors. Moreover, circadian misalignment, such as that experienced by "shift workers" has been shown to be associated with an increased incidence of several malignancies including, breast, colorectal and prostate cancer, consistent with the increasing recognition of the role of clock genes in the metabolic processes. Of increasing concern is the accelerating incidence of sleep disorders in childhood, their association with childhood obesity and associated abnormalities of circulating cytokines, adipokines and metabolic factors, many of which are implicated as etiologic mediators of the connection between obesity and cancer. Extensive studies have now been initiated to investigate the mechanisms by which disturbances in sleep duration, sleep continuity and sleep related breathing affect circadian rhythm, central and peripheral tissue oxygenation and metabolism, quality and quantity of dietary intake and circulating inflammatory cytokines and regulatory hormones. This volume aims to present the latest research on sleep, sleep disturbance and its correlation to obesity and cancer.

Sleep Loss and Obesity: Intersecting Epidemics represents a major contribution to the field of sleep medicine. It is a comprehensive review of the neurobiology of sleep, circadian timing and obesity, the deleterious effects of sleep loss and obesity on health, and the worrisome associated social and medical costs in a range of patient populations and overall to society. The number of individuals who are obese has reached alarming levels. As a result, the incidence of Type 2 diabetes, cardiovascular disorders, heart disease, and kidney failure have also increased. The surgeon general estimates that the total annual cost of obesity in the US is about $117 billion. This cost is expected to escalate significantly because the number of overweight and obese children is increasing rapidly. Indeed, the new generation is expected to have a shorter life-span then their parents. In addition, sleep loss is emerging as an important contributing factor to obesity. People who sleep less or are sleep deprived tend to eat more, especially carbohydrates, and have a higher body mass index. Increased weight restricts the upper airway, causing obstructive sleep apnea and further sleep loss. In the end there is a vicious cycle of weight gain and sleep loss. In the past few years there has been a tremendous growth in our understanding of brain mechanisms controlling energy metabolism. Interestingly the neurons regulating waking also regulate feeding. There is also a mechanism that regulates the timing of feeding and sleep. In shift-workers this system is likely to be disturbed, and this has an adverse impact on both feeding and sleep. Sleep Loss and Obesity: Intersecting Epidemics is the first title to clearly examine how obesity and sleep loss are interacting epidemics. This fascinating title makes the link between energy metabolism, sleep and circadian timing; identifies poor sleep as a risk-factor for obesity in children and adults and offers treatment strategies for obstructive sleep apnea and obesity. This book will be a vital source of information for all physicians interested in sleep disorders and obesity. It will also be of value to neuroscientists, health system administrators, and policy makers.

Learn to think mathematically and develop genuine problem-solving skills with COLLEGE ALGEBRA, Seventh Edition. This straightforward and easy-to-use book will help you learn the fundamentals of algebra in a variety of practical ways. The book features new tools to help you succeed, such as learning objectives before each section to prepare you for what you're about to learn, and a list of formulas and key concepts after each section that help reinforce what you've learned. In addition, the book includes many real-world examples that show you how mathematics is used to model in fields like engineering, business, physics, chemistry, and biology.

Das Buch gibt eine leicht verstandliche Einfuhrung in die Thematik der Technischen Informatik, die heute fur das Verstandnis technischer Hard- und Softwaresysteme unverzichtbar ist. Zahlreiche Abbildungen sollen technische Zusammenhange in Computersystemen verdeutlichen. Folgende Themenbereiche werden behandelt: * Entwurf logischer Schaltungen * Very High Speed Integrated Circuit Hardware Description Language (VHDL) * Endliche Automaten * Mikroprozessoren * Computersysteme * Betriebssysteme und Systemsoftware * Programmprozesse * Speicherverwaltung * Interprozess-Kommunikation * Netzwerke * Resource-Management * Sicherheit in Betriebssystemen Die Neuauflage wurde um ein Kapitel uber USB und Firewire sowie um eines uber Netzwerke erganzt. Das Kapitel "Betriebssysteme" wurde um einen Abschnitt "Sicherheit" erweitert.

This concise and comprehensive resource is vital for the pathologist faced with providing accurate, timely, and clinically useful diagnoses for placentas, products of conception, and gravid hysterectomies. Combining the pathologic, research, and clinical expertise of a diverse group of editors and authors from centers of excellence for placental pathology, this book enables easy application of the latest Amsterdam international consensus classification criteria, with cross-references to previous terminology and a pathophysiology-based classification system. It provides complete descriptions and illustrations of diagnostic gross, microscopic, and immunohistochemical findings together with a thorough discussion of potential pitfalls and differential diagnosis. Current theories of the genetic and physiologic basis for disease processes, culminating in placental lesions are discussed. The book features high-quality images and standardized measurement tables to assist real-time diagnoses and provides access to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.