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Polymers for Pharmaceutical and Biomedical Applications:
Fundamentals, Selection, and Preparation supports the successful
selection, design, and development of polymers with the required
properties and performance for a range of advanced pharmaceutical
and biomedical applications. The book begins by introducing
polymers for pharmaceutical and biomedical applications, examining
classification, basic properties, structures, and grades. This is
followed by in-depth chapters focusing on synthesis and
modification, characterization techniques, and dissolution and
solubility of polymers for pharmaceutical applications. Key
applications are then highlighted, with chapters explaining in
detail the preparation of polymers for conventional dosage,
modified drug delivery, conjugates, advanced drug and gene
delivery, medical devices, pharmaceutical packaging, tissue
engineering, artificial organs, and dentistry. Throughout the book,
the aim is to provide accessible, step-by-step coverage, supported
by diagrams and case studies. Finally, safety and regulatory
aspects are discussed. This is a valuable resource for all those
who are newly approaching the field of polymers and product
development for pharmaceutical and biomedical applications. This
includes researchers and advanced students across polymer science,
pharmaceutical science, biomaterials, biomedicine, healthcare, and
chemistry, and scientists and R&D professionals in an
industrial setting.
A Handbook of Artificial Intelligence in Drug Delivery explores the
use of Artificial Intelligence (AI) in drug delivery strategies.
The book covers pharmaceutical AI and drug discovery challenges,
Artificial Intelligence tools for drug research, AI enabled
intelligent drug delivery systems and next generation novel
therapeutics, broad utility of AI for designing novel
micro/nanosystems for drug delivery, AI driven personalized
medicine and Gene therapy, 3D Organ printing and tissue
engineering, Advanced nanosystems based on AI principles
(nanorobots, nanomachines), opportunities and challenges using
artificial intelligence in ADME/Tox in drug development,
commercialization and regulatory perspectives, ethics in AI, and
more. This book will be useful to academic and industrial
researchers interested in drug delivery, chemical biology,
computational chemistry, medicinal chemistry and bioinformatics.
The massive time and costs investments in drug research and
development necessitate application of more innovative techniques
and smart strategies.
Applications of Polymers in Drug Delivery, Second Edition, provides
a comprehensive resource for anyone looking to understand how
polymeric materials can be applied to current, new, and emerging
drug delivery applications. Polymers play a crucial role in
modulating drug delivery and have been fundamental in the
successful development of many novel drug delivery systems. This
book describes the development of polymeric systems, ranging from
conventional dosage forms to the most recent smart systems.
Regulatory and intellectual property aspects as well as the
clinical applicability of polymeric drug delivery systems are also
discussed. The chapters are organized by specific delivery route,
offering methodical and detailed coverage throughout. This second
edition has been thoroughly revised to include the latest
developments in the field. This is an essential book for
researchers, scientists, and advanced students, in polymer science,
drug delivery, pharmacology/pharmaceuticals, materials science,
tissue engineering, nanomedicine, chemistry, and biology. In
industry, this book supports scientists, R&D, and other
professionals, working on polymers for drug delivery applications.
The application of drug delivery is a valuable, cost-effective
lifecycle management resource. By endowing drugs with new and
innovative therapeutic benefits, drug delivery systems extend
products' profitable lifecycle, giving pharmaceutical companies
competitive and financial advantages, and providing patients with
improved medications. Formulation development is now being used to
create new dosage forms for existing products, which not only
reduces the time and expense involved in new drug development, but
also helps with regard to patent protection and bypassing existing
patents. Today's culture demands convenience, a major factor
determining adherence to drug therapy. Over the past few years,
patient convenience-oriented research in the field of drug delivery
has yielded a range of innovative drug-delivery options. As a
result, various drug-delivery systems, including medicated chewing
gums, oral dispersible tablets, medicated lozenges and lollipops,
have now hit the market and are very popular. These dosage forms
offer a highly convenient way to dose medications, not only for
special population groups with swallowing difficulties, such as
children and the elderly, but for the general populace as well.
This book provides valuable insights into a number of formulation
design approaches that are currently being used, or could be used,
to provide new benefits from existing drug molecules.
This book covers the essentials of drug delivery research and
provides a unique forum for scientific experimental methods that
are exclusively focused by the in-vitro, ex-vivo, and in-vivo
methodologies of drug delivery research and felicitates
translational research. The book includes recent and novel
approaches in evaluation methods of transdermal, nasal, ocular,
oral and intraoral, gastro-retentive, colon-targeted, and
brain-targeted drug delivery systems. Providing up to date and
comprehensive information, this text is invaluable to students,
teachers, scientists, and others employed in the field of drug
delivery.
The application of drug delivery is a valuable, cost-effective
lifecycle management resource. By endowing drugs with new and
innovative therapeutic benefits, drug delivery systems extend
products' profitable lifecycle, giving pharmaceutical companies
competitive and financial advantages, and providing patients with
improved medications. Formulation development is now being used to
create new dosage forms for existing products, which not only
reduces the time and expense involved in new drug development, but
also helps with regard to patent protection and bypassing existing
patents. Today's culture demands convenience, a major factor
determining adherence to drug therapy. Over the past few years,
patient convenience-oriented research in the field of drug delivery
has yielded a range of innovative drug-delivery options. As a
result, various drug-delivery systems, including medicated chewing
gums, oral dispersible tablets, medicated lozenges and lollipops,
have now hit the market and are very popular. These dosage forms
offer a highly convenient way to dose medications, not only for
special population groups with swallowing difficulties, such as
children and the elderly, but for the general populace as well.
This book provides valuable insights into a number of formulation
design approaches that are currently being used, or could be used,
to provide new benefits from existing drug molecules.
This book covers the essentials of drug delivery research and
provides a unique forum for scientific experimental methods that
are exclusively focused by the in-vitro, ex-vivo, and in-vivo
methodologies of drug delivery research and felicitates
translational research. The book includes recent and novel
approaches in evaluation methods of transdermal, nasal, ocular,
oral and intraoral, gastro-retentive, colon-targeted, and
brain-targeted drug delivery systems. Providing up to date and
comprehensive information, this text is invaluable to students,
teachers, scientists, and others employed in the field of drug
delivery.
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