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Cholangiocarcinoma is the second most frequent primary neoplasm of the liver and its incidence is increasing in Western countries. These neoplasms arise from the biliary tract and can be categorized according to their anatomical location as intrahepatic and extrahepatic cholangiocarcinomas. The prognosis of these neoplasms is poor and most patients are not suitable for curative resection at the time of diagnosis, due to advanced stage of tumor. Complete surgical resection still remains the only effective and potentially curative therapy. Both intrahepatic and hilar cholangiocarcinoma often requires major liver resection to obtain a radical treatment. In recent years the improvements in non- invasive diagnostic imaging modalities, a better understanding of liver anatomy, the improvements of preoperative optimisation of liver function (preoperative biliary drainage, portal vein embolization), the increased safety of liver surgery have gradually improved the outcome. Moreover, aggressive surgical approach could increase curative surgery. Still now the role of adjunvant therapies and liver transplantation are not well clarified. This book contains an up-to-date review of diagnostic and staging tools of cholangiocarcinoma, a guide to optimal selection of therapeutic modalities and a review of long-term outcome of surgery and liver transplantation. Moreover, it provides details of surgical techniques and principles for curative and palliative surgery. This book will appeal to physicians and hepatobiliary surgeons who want to improve their knowledge about surgical management of intrahepatic and hilar cholangiocarcinomas.
La (TM)ecografia A] una metodica particolarmente indicata per guidare le procedure interventistiche. La (TM)ecografia interventistica viene spesso impiegata per la diagnosi di malattia. Notevoli e rapidi avanzamenti tecnologici hanno portato alla sempre maggiore diffusione delle procedure interventistiche ecoguidate, modificando in modo significativo le strategie diagnostiche e terapeutiche di molte patologie. Il volume presenta una concisa panoramica delle piA comuni procedure interventistiche percutanee e si propone come guida rapida per il radiologo e la (TM)ecografista ai quali, sempre piA frequentemente, viene richiesta la (TM)esecuzione di procedure interventistiche su fegato, vie biliari e pancreas sia per fini diagnostici che terapeutici. La trattazione A] estesa anche ad altre metodiche di imaging ad integrazione, completamento o quale alternativa alla guida ecografica. Se da un lato A] infatti sempre piA sentita la necessitA di svolgere il ruolo di interventista, dalla (TM)altro risulta indispensabile la competenza nella scelta e nella (TM)impiego della metodica piA adeguata per la corretta realizzazione della procedura richiesta in relazione allo specifico quesito (diagnosi, terapia e follow-up).
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