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Collectively known as the alloimmune cytopenias, hemolytic disease
of the fetus and newborn, alloimmune thrombocytopenia and
alloimmune neutropenia are all consequences of maternal
immunisation to fetal blood cells. The effective prevention,
diagnosis and management of these disorders has become a team
effort involving haematologists, obstetricians, paediatricians,
immunologists, laboratory technicians, midwives and research
scientists. This book has been written by experts in their
respective fields to bring together the issues of pathogenesis,
epidemiology, prevention, diagnosis and clinical management. This
comprehensive but accessible account is extensively
cross-referenced to emphasise the links between pathogenesis and
clinical sequelae, between epidemiology and the rationale for
screening programmes, and between diagnosis and therapeutic
intervention. This is an authoritative overview suitable for
trainees in obstetrics, materno-fetal medicine, transfusion
medicine and clinical immunology.
The effective prevention, diagnosis, and management of alloimmune cytopenias has become a team effort involving hematologists, obstetricians, pediatricians, immunologists, laboratory technicians, midwives, and research scientists. This book has been written by experts in their respective fields to bring together the issues of pathogenesis, epidemiology, prevention, diagnosis, and clinical management. This comprehensive but accessible account is extensively cross-referenced to emphasize the links between pathogenesis and clinical sequels, between epidemiology and the rationale for screening programs, and between diagnosis and therapeutic intervention.
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