This volume discusses the vaccine development process and the role delivery concepts contribute to a global goal of effective health outcomes. The chapters in this book cover a wide range of topics such as antigen discovery methods; genetic and protein antigen preparation; preparation of viral vaccines as VLPs; viral and non-viral gene delivery; needle-less or non-invasive delivery technology; vaccine storage; and vaccine administration and assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step, readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vaccine Delivery Technology: Methods and Protocols is a valuable resource for both novice and expert researchers, in and outside the field, who would like to gain insight into the impactful field of vaccines. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

In a rapidly changing world, businesses must create a high-performing, metrics-driven workplace environment characterized by respect, inclusion, teamwork, innovation, and overall harmony—and it must be manageable and sustainable. This book shows that returning to managerial basics will provide the way forward, as exemplified by legendary UCLA basketball coach John Wooden, the model for a new people management pathway: the SCORE paradigm. Generally considered the greatest coach in history, John Wooden’s recipe for team success was unique, culture-based, and ahead of its time. Building upon Wooden’s 21 coaching principles and his own 35 years of experience as a human resources leader, Bill Kane has created the SCORE framework to guide people managers in creating and nurturing effective teams, and steering their organizations through times of change: • Staffing: Attracting and Selecting Talent • Cultivating Culture: Defining How People Should Interact • Organizing and Planning: The Need for Direction and Focus • Reinforcing Desirable Behavior: Managing Performance • Engaging the Organization: A Leader’s Role and Responsibility Enlivened with stories from the careers of Coach Wooden, Andy Hill (a three-time national champion under Coach), and the author, the book clearly explains why each coaching principle works in practice, and provides examples of success, as well as pitfalls to avoid. Readers will learn how to get the right people on their team, create meaningful participative and inclusive management practices, build a winning organizational culture, and achieve heightened results. New and experienced people managers and leaders in corporate settings, as well as business and organizational psychology students, will appreciate this timeless reference tool, a roadmap to help people managers –as their own “work-in-progress� – develop strategies for success based upon a proven and simple model.

In a rapidly changing world, businesses must create a high-performing, metrics-driven workplace environment characterized by respect, inclusion, teamwork, innovation, and overall harmony—and it must be manageable and sustainable. This book shows that returning to managerial basics will provide the way forward, as exemplified by legendary UCLA basketball coach John Wooden, the model for a new people management pathway: the SCORE paradigm. Generally considered the greatest coach in history, John Wooden’s recipe for team success was unique, culture-based, and ahead of its time. Building upon Wooden’s 21 coaching principles and his own 35 years of experience as a human resources leader, Bill Kane has created the SCORE framework to guide people managers in creating and nurturing effective teams, and steering their organizations through times of change: • Staffing: Attracting and Selecting Talent • Cultivating Culture: Defining How People Should Interact • Organizing and Planning: The Need for Direction and Focus • Reinforcing Desirable Behavior: Managing Performance • Engaging the Organization: A Leader’s Role and Responsibility Enlivened with stories from the careers of Coach Wooden, Andy Hill (a three-time national champion under Coach), and the author, the book clearly explains why each coaching principle works in practice, and provides examples of success, as well as pitfalls to avoid. Readers will learn how to get the right people on their team, create meaningful participative and inclusive management practices, build a winning organizational culture, and achieve heightened results. New and experienced people managers and leaders in corporate settings, as well as business and organizational psychology students, will appreciate this timeless reference tool, a roadmap to help people managers –as their own “work-in-progress� – develop strategies for success based upon a proven and simple model.

Childhood Obesity Prevention and Treatment, Second Edition summarizes the latest scientific knowledge on obesity in children. This edition focuses on the developmental aspects of obesity, especially on the influences and factors predisposing individuals to obesity from early periods of life. This new body of knowledge stems from both basic research and recent epidemiological and clinical studies. All chapters are updated and special attention is given to the prevention of obesity in the context of developmental physiology, lifestyle modification, and dietary and physical activity approaches. Highlighting the most recent research, this timely book covers a broad range of aspects related to the prevention and management of childhood obesity. It emphasizes early intervention and an integrated behavioral approach to overcome the ongoing challenge of this global epidemic. Features * Updates all chapters and includes new research on growing populations of obesity in the Third World * Provides information on promoting health as a means to reduce obesity * Focuses on the developmental aspects of obesity

Good leaders walk a tightrope between doing and daring - often in the glare of the public spotlight. In Leadership in the Headlines, Andrew Hill, the award-winning Management Editor of the Financial Times, shares his insider insights into the who's and how's of effective leadership. Packed with practical lessons, this book divides the best of Andrew's wry and insightful columns into eight 'acts' of leadership, with new commentary enhancing each one. Whether you're new to Andrew Hill's columns or a loyal reader, you'll gain fresh perspectives on the tough job of leading and take away tips about how to refine your own management skills.

Childhood Obesity Prevention and Treatment, Second Edition summarizes the latest scientific knowledge on obesity in children. This edition focuses on the developmental aspects of obesity, especially on the influences and factors predisposing individuals to obesity from early periods of life. This new body of knowledge stems from both basic research and recent epidemiological and clinical studies. All chapters are updated and special attention is given to the prevention of obesity in the context of developmental physiology, lifestyle modification, and dietary and physical activity approaches.

Highlighting the most recent research, this timely book covers a broad range of aspects related to the prevention and management of childhood obesity. It emphasizes early intervention and an integrated behavioral approach to overcome the ongoing challenge of this global epidemic.

Features

- Updates all chapters and includes new research on growing populations of obesity in the Third World

- Provides information on promoting health as a means to reduce obesity

- Focuses on the developmental aspects of obesity

This monograph presents the results of over 10 years of paleontological and geological survey in the Baynunah Formation of the United Arab Emirates. Exposed widely in western Abu Dhabi Emirate, the Baynunah Formation and its fossils provide the only record of terrestrial environments and evolution in the Arabian Peninsula during the late Miocene epoch (12-5 Ma). This volume describes new fossils collected since 2002, presented systematically by taxon, and including mammals, reptiles, and invertebrates, as well as fossil trackways. The discoveries are framed within the results of new geological, geochemical, and geochrononological analyses, providing an updated and synthetic view of the age, environments, and biogeographic relationships of this important fossil assemblage.

The Ruskin Society Book of The Year. Who was John Ruskin? What did he achieve - and how? Where is he today? One possible answer: almost everywhere. John Ruskin was the Victorian age's best-known and most controversial intellectual. He was an art critic, a social activist, an early environmentalist; he was also a painter, writer, and a determined tastemaker in the fields of architecture and design. His ideas, which poured from his pen in the second half of the 19th century, sowed the seeds of the modern welfare state, universal state education and healthcare free at the point of delivery. His acute appreciation of natural beauty underpinned the National Trust, while his sensitivity to environmental change, decades before it was considered other than a local phenomenon, fuelled the modern green movement. His violent critique of free market economics, Unto This Last, has a claim to be the most influential political pamphlet ever written. Ruskin laid into the smug champions of Victorian capitalism, prefigured the current debate about inequality, executive pay, ethical business and automation. Gandhi is just one of the many whose lives were changed radically by reading Ruskin, and who went on to change the world. This book, timed to coincide with the 200th anniversary of John Ruskin's birth in 2019, will retrace Ruskin's steps, telling his life story and visiting the places and talking to the people who - perhaps unknowingly - were influenced by Ruskin himself or by his profoundly important ideas. What, if anything, do they know about him? How is what they do or think linked to the vivid, difficult but often prophetic pronouncements he made about the way our modern world should look, live, work and think? As important, where - and why - have his ideas been swept away or displaced, sometimes by buildings, developments and practices that Ruskin himself would have abhorred? Part travelogue, part quest, part unconventional biography, this book will attempt to map Ruskinland: a place where, two centuries after John Ruskin's birth, more of us live than we know.

Excellent social work education and training is vital for ensuring best practice, and it is important to understand the key approaches and methods in order to provide the best teaching and ensure effective learning. This volume provides an overview of social work education, including the background and current context. It covers the key debates surrounding social work education, such as the evaluation of social work education, the use of IT, research-mindedness, and the effectiveness of interdisciplinary education. The book also offers guidance on effective teaching and learning approaches tailored to the needs of social work educators, covering teaching within a higher education institution, on student practice placements, and in post-qualifying settings. This will be an indispensable text for educators and trainers in the field of social work.

""I was determined to change my life in accordance with the ideals of the book." --Gandhi on" Unto this Last"" One of the most influential political essays ever written, "Unto this Last "was one of the defining texts of British socialism and reading it was a decisive experience in the lives of Gandhi (who translated it into Gujarati) and Martin Luther King, among many others. Ruskin's lessons are as urgently needed today as ever, as his attack on the greed and short-termism of unbridled capitalism, and on the pursuit of money instead of true wealth, are every bit as inspiring and challenging as they were when it was published 150 years ago. A new introduction by Andrew Hill discusses the value of the essay in an age of credit crunch. A foreword by the Master of the Guild of St. George, Ruskin's association for social reform, sets out what Ruskinians today can do and are doing.

While Apple provides a modicum of documentation for developers just starting with WebObjects, more-skilled WebObjects developers typically learn from each other or via trial and error. Practical WebObjects formalizes this process for the skilled and experienced WebObjects developer with this 100% pragmatic resource. Written by two expert WebObjects developers, Charles Hill and Sacha Mallais, this book features working, world-tested solutions for difficult problems. Endorsed by Global Village, Practical WebObjects includes many topics not covered anywhere else, including localization, validation, and optimization. Practical WebObjects will prove invaluable for WebObjects developers trying to solve specific problems and wanting to increase their overall knowledge of WebObjects.

This monograph presents the results of over 10 years of paleontological and geological survey in the Baynunah Formation of the United Arab Emirates. Exposed widely in western Abu Dhabi Emirate, the Baynunah Formation and its fossils provide the only record of terrestrial environments and evolution in the Arabian Peninsula during the late Miocene epoch (12-5 Ma). This volume describes new fossils collected since 2002, presented systematically by taxon, and including mammals, reptiles, and invertebrates, as well as fossil trackways. The discoveries are framed within the results of new geological, geochemical, and geochrononological analyses, providing an updated and synthetic view of the age, environments, and biogeographic relationships of this important fossil assemblage.

Archaeological data from the Late Archaic (4000-2000 years ago) in the Western Great Lakes are analyzed to understand the production and movement of copper and lithic exchange materials. Also considered in this volume are access to and benefits from exchange networks, as well as social changes accompanying the development of extensive, continental scale, exchange systems of interaction in this period.

This volume discusses the vaccine development process and the role delivery concepts contribute to a global goal of effective health outcomes. The chapters in this book cover a wide range of topics such as antigen discovery methods; genetic and protein antigen preparation; preparation of viral vaccines as VLPs; viral and non-viral gene delivery; needle-less or non-invasive delivery technology; vaccine storage; and vaccine administration and assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step, readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vaccine Delivery Technology: Methods and Protocols is a valuable resource for both novice and expert researchers, in and outside the field, who would like to gain insight into the impactful field of vaccines. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Despite the return of the Hebrews from the Babylonian exile, selfishness, apathy and despair crippled their community spirit. In response to this distress, God raised up three prophetic voices in Jerusalem. Haggai rallied the people to rebuild the Second Temple. Zechariah was given visions of the return of the glory of the Lord to Zion. Malachi preached repentance, covenant justice and restoration of proper temple worship. Andrew Hill's excellent commentary on these oracles shows how they remain timely for the Christian church's worship and mission in the world.