What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

The Anthropocene defines the here-and-now time period on Earth of indelible (and possibly irreversible) human disturbance to the natural world, from habitat destruction and mass extinction to global climate change. To ameliorate and repair the damage that threatens the world's dwindling resources and our very existence, humanity is enacting massive interventions to fuse modern technologies with long established natural processes. Advances in genetic engineering have put us on the cusp of directly shaping the DNA of every living organism (including ourselves), as well as determining the evolution of completely novel species. The author invites the reader to explore how humans have manipulated the ancient forces of evolution and the future possibilities of genetic engineering for conservation and rewilding, de-extinction, and even the creation of viable populations of entirely new species. To entertain such possibilities of synthetic biology, he forces us to wrestle with the threats and ethical conundrums that surround the unintended consequences, as well as the values that humanity places on authenticity in nature. In so doing, this accessible and thought-provoking book explores the potential future of life on planet Earth.

What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.