Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.

Any cutaneous insult results in wound healing and wound healing results in formation of a scar. Human cutaneous scars represent a very important problem in clinical practice. Human cutaneous scars cause both cosmetic and medical problems in people who have them. There are various types of human cutaneous scars: physiologic normotrophic scars, atrophic scars, and proliferative scars. Additionally, there are scar complications that physicians must deal with. Scar complications include unstable scars, contractures and even development of malignancy at worst. Treatment of scars is also challenging especially in case of development of abnormal scars. Human cutaneous scars have various aspects of interest such as biology, clinical significance, patient perspective, prevention, and treatment. There are various preclinical models for studying them. Scarless healing is another item of interest that is observed in fetal wound healing and in some animals. There are various studies specifically examining the biology and the treatment of proliferative scars. The cutaneous scars are very common so every physician will face a cutaneous scar-related problem in his/her medical practice. The significance is indicated by the frequency of burn injury and traffic accidents and by the importance of incision scars for any surgeon. The editors of this book have enormous experience in the clinical management of human cutaneous scars. The editors also studied the biology of abnormal scarring by developing new animal models. The editors also have performed clinical studies to increase therapeutic options for the treatment of abnormal scars. In this hardcover book, the aim is to examine human cutaneous scars in every aspect: historical aspects, clinical significance, biology, laboratory and animal models, histopathology, scarless healing, scar complications, and treatment. In this book, all the available treatment methods are examined in detail.