This book is written for researchers and students interested in the function and role of chemical elements in biological or environmental systems. Experts have long known that the Periodic System of Elements (PSE) provides only an inadequate chemical description of elements of biological, environmental or medicinal importance. This book explores the notion of a Biological System of the Elements (BSE) established on accurate and precise multi-element data, including evolutionary aspects, representative sampling procedures, inter-element relationships, the physiological function of elements and uptake mechanisms. The book further explores the concept Stoichiometric Network Analysis (SNA) to analyze the biological roles of chemical species. Also discussed is the idea of ecotoxicological identity cards which give a first-hand description of properties relevant for biological and toxicological features of a certain chemical element and its geo biochemically plausible speciation form. The focus of this book goes beyond both classical bioinorganic chemistry and toxicology.

Modern computational techniques, such as the Finite Element Method, have, since their development several decades ago, successfully exploited continuum theories for numerous applications in science and technology. Although standard continuum methods based upon the Cauchy-Boltzmann continuum are still of great importance and are widely used, it increasingly appears that material properties stemming from microstructural phenomena have to be considered. This is particularly true for inhomogeneous load and deformation states, where lower-scale size effects begin to affect the macroscopic material response; something standard continuum theories fail to account for. Following this idea, it is evident that standard continuum mechanics has to be augmented to capture lower-scale structural and compositional phenomena, and to make this information accessible to macroscopic numerical simulations.

This book is written for researchers and students interested in the function and role of chemical elements in biological or environmental systems. Experts have long known that the Periodic System of Elements (PSE) provides only an inadequate chemical description of elements of biological, environmental or medicinal importance. This book explores the notion of a Biological System of the Elements (BSE) established on accurate and precise multi-element data, including evolutionary aspects, representative sampling procedures, inter-element relationships, the physiological function of elements and uptake mechanisms. The book further explores the concept Stoichiometric Network Analysis (SNA) to analyze the biological roles of chemical species. Also discussed is the idea of ecotoxicological identity cards which give a first-hand description of properties relevant for biological and toxicological features of a certain chemical element and its geo biochemically plausible speciation form. The focus of this book goes beyond both classical bioinorganic chemistry and toxicology.

Modern computational techniques, such as the Finite Element Method, have, since their development several decades ago, successfully exploited continuum theories for numerous applications in science and technology. Although standard continuum methods based upon the Cauchy-Boltzmann continuum are still of great importance and are widely used, it increasingly appears that material properties stemming from microstructural phenomena have to be considered. This is particularly true for inhomogeneous load and deformation states, where lower-scale size effects begin to affect the macroscopic material response; something standard continuum theories fail to account for. Following this idea, it is evident that standard continuum mechanics has to be augmented to capture lower-scale structural and compositional phenomena, and to make this information accessible to macroscopic numerical simulations.