This book contains contributions of leading international scientists who participated at the NATO-ASI conference 'Stem cells and their potential for clinical application' that was held in Kiev and Simeiz (Ukraine) from August 23 - 31, 2006. The articles cover a broad range of hot topics in stem cell and leukaemia research. Those include the potential of various stem cell types in regenerative and transplantation medicine, different mechanisms of malignant transformation leading to leukaemia development, as well as novel clinical strategies for malignant disease treatment such as adoptive immunotherapy with gene-modified lymphocytes. The mixture of articles by principal scientists from Northern America, as well as Eastern and Western Europe, provides a comprehensive overview on 'What's going on' in various parts of the world in such broadly discussed fields as 'stem cell research', 'immunotherapy' or 'gene therapy'.

This book contains contributions of leading international scientists who participated at the NATO-ASI conference Stem cells and their potential for clinical application that was held in Kiev and Simeiz (Ukraine) from August 23 - 31, 2006. The articles cover a broad range of hot topics in stem cell and leukaemia research. These include the potential of various stem cell types in regenerative and transplantation medicine, different mechanisms of malignant transformation leading to leukaemia development, as well as novel clinical strategies for malignant disease treatment such as adoptive immunotherapy with gene-modified lymphocytes. The mixture of articles by principal scientists from Northern America, as well as Eastern and Western Europe, provides a comprehensive overview on area such as stem cell research, immunotherapy and gene therapy. Thus, this compilation should be valuable for readers interested in modern biomedicine who have background knowledge in those areas.

Dieses essential gibt einen UEberblick uber Grundlagen sowie Chancen und Risiken der Gentherapie, mit besonderem Fokus auf das Genome Editing. Es werden aktuelle und zukunftige klinische Anwendungen der neuen, mit vielen Hoffnungen, aber auch AEngsten verbundenen Technologien diskutiert.