Methodological problems have hampered researchers' efforts to understand and control AIDS since the beginning of the epidemic. This practical book addresses these problems by using actual health research case studies to develop strategies regarding design and sampling, measurement, and analysis and modeling issues. Researchers working on both biological and behavioral aspects of the disease will find this work a singularly effective tool to improve their study designs.

On any given day, nearly half a million children are served by foster care services in the U.S. at an annual cost of over $25 billion. Growing demand and shrinking funds have so greatly stressed the child welfare system that calls for orphanages have re-entered the public debate for the first time in nearly half a century. New ideas are desperately needed to transform a system in crisis, guarantee better outcomes for children in foster care, and reduce the need for out-of-home care in the first place. Yet little is known about what works in foster care. Very few studies have examined how alumni have fared as adults or tracked long-term health effects, and even fewer have directly compared different foster care services. In one of the most comprehensive studies of adults formerly in foster care ever conducted, the Northwest Foster Care Alumni Study found that quality foster care services for children pay big dividends when they grow into adults. Key investments in highly trained staff, low caseloads, and robust supplementary services can dramatically reduce the rates of mental disorders and substance abuse later in life and increase the likelihood of completing education beyond high school and remaining employed. The results of this unparalleled study document not only the more favorable outcomes for youth who receive better services but the overall return when an investment is made in high quality foster care: every dollar invested in a child generates $1.50 in benefits to society. These findings form the core of this book's blueprint for reform. By keeping more children with their families and investing additional funds in enhanced foster care services, child welfare agencies have the opportunity to greatly improve the health, well being, and economic prospects for foster care alumni. What Works in Foster Care? presents a model foster care program that promises to revolutionize the way policymakers, administrators, case workers, and researchers think about protecting our most vulnerable youth.

Mental disorders have profound social, cultural, and economic effects throughout the world. Although most psychiatry and psychology texts provide some basic data on the prevalence and treatment of mental disorders, no previous book has ever presented such data with the breadth or depth of the current volume.
Reported here are the first results of the WHO World Mental Health (WMH) Survey Initiative, the largest coordinated series of cross-national psychiatric epidemiological surveys ever undertaken. The general population surveys in the WMH series span 17 countries in all parts of the world. In many of these countries the WMH surveys provide the first community epidemiological data ever available on mental disorders in the population. The detailed information on lifetime prevalence, age of onset, course, correlates, and treatment of mental disorders in this volume provides mental health professionals and healthcare policy planners with an unprecedented state-of-the-art reference on the cross-national descriptive epidemiology of mental disorders.

This comprehensive and well-established cartography textbook covers the theory and the practical applications of map design and the appropriate use of map elements. It explains the basic methods for visualizing and analyzing spatial data and introduces the latest cutting-edge data visualization techniques. The fourth edition responds to the extensive developments in cartography and GIS in the last decade, including the continued evolution of the Internet and Web 2.0; the need to analyze and visualize large data sets (commonly referred to as Big Data); the changes in computer hardware (e.g., the evolution of hardware for virtual environments and augmented reality); and novel applications of technology. Key Features of the Fourth Edition: Includes more than 400 color illustrations and it is available in both print and eBook formats. A new chapter on Geovisual Analytics and individual chapters have now been dedicated to Map Elements, Typography, Proportional Symbol Mapping, Dot Mapping, Cartograms, and Flow Mapping. Extensive revisions have been made to the chapters on Principles of Color, Dasymetric Mapping, Visualizing Terrain, Map Animation, Visualizing Uncertainty, and Virtual Environments/Augmented Reality. All chapters include Learning Objectives and Study Questions. Provides more than 250 web links to online content, over 730 references to scholarly materials, and additional 540 references available for Further Reading. There is ample material for either a one or two-semester course in thematic cartography and geovisualization. This textbook provides undergraduate and graduate students in geoscience, geography, and environmental sciences with the most valuable up-to-date learning resource available in the cartographic field. It is a great resource for professionals and experts using GIS and Cartography and for organizations and policy makers involved in mapping projects.

Methodological problems have hampered researchers' efforts to understand and control AIDS since the beginning of the epidemic. This practical book addresses these problems by using actual health research case studies to develop strategies regarding design and sampling, measurement, and analysis and modeling issues. Researchers working on both biological and behavioral aspects of the disease will find this work a singularly effective tool to improve their study designs.

The new field of applied genetic research, genetic toxicology and mutation research investigates the mutagenicity and cancerogenicity of chemicals and other agents. Permanent changes in genes and chromosomes, or genome mutations, can be induced by a plethora of agents, including ionizing and nonionizing radiations, chemicals, and viruses. Mutagenesis research has two aims: (1) to understand the molecular mechanisms leading to mutations, and (2) to prevent a thoughtless introduction of mutagenic agents into our environment. Both aspects, namely, basic and applied, will be treated in the new series Advances in Mutagenesis Research.

AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

Demons of the Night is a trove of haunting fiction--a gathering, for the first time in English, of the best nineteenth-century French fantastic tales. Featuring such authors as Balzac, Merimee, Dumas, Verne, and Maupassant, this book offers readers familiar with the works of Edgar Allan Poe and E. T. A. Hoffman some of the most memorable stories in the genre. With its aura of the uncanny and the supernatural, the fantastic tale is a vehicle for exploring forbidden themes and the dark, irrational side of the human psyche. The anthology opens with Smarra, or the Demons of the Night, Nodier's 1821 tale of nightmare, vampirism, and compulsion, acclaimed as the first work in French literature to explore in depth the realm of dream and the unconscious. Other stories include Balzac's The Red Inn, in which a crime is committed by one person in thought and another in deed, and Merimee's superbly crafted mystery, The Venus of Ille, which dramatizes the demonic power of a vengeful goddess of love emerging out of the pagan past. Gautier's protagonist in The Dead in Love develops an obsessive passion for a woman who has returned from beyond the grave, while the narrator of Maupassant's The Horla imagines himself a victim of psychic vampirism. Joan Kessler has prepared new translations of nine of the thirteen tales in the volume, including Gerard de Nerval's odyssey of madness, Aurelia, as well as two tales that have never before appeared in English. Kessler's introduction sets the background of these tales--the impact of the French Revolution and the Terror, the Romantics' fascination with the subconscious, and the influence of contemporary psychological and spiritual currents. Her essay illuminates how each of the authors in this collection used the fantastic to articulate his own haunting obsessions as well as his broader vision of human experience.

Mental disorders have profound social, cultural, and economic effects throughout the world. Although most psychiatry and psychology texts provide some basic data on the prevalence and treatment of mental disorders, no previous book has ever presented such data with the breadth or depth of the current volume.
Reported here are the first results of the WHO World Mental Health (WMH) Survey Initiative, the largest coordinated series of cross-national psychiatric epidemiological surveys ever undertaken. The general population surveys in the WMH series span 17 countries in all parts of the world. In many of these countries the WMH surveys provide the first community epidemiological data ever available on mental disorders in the population. The detailed information on lifetime prevalence, age of onset, course, correlates, and treatment of mental disorders in this volume provides mental health professionals and healthcare policy planners with an unprecedented state-of-the-art reference on the cross-national descriptive epidemiology of mental disorders.

This book is a resource for health and social scientists who assess the role of stress in their studies of physical and psychiatric illness. This work discusses how stress is conceptualized, the pathways through which stressors influence the onset and progression of psychiatric and physical illness, the alternate methods of measuring stress, and how one decides on appropriate measurement.

On the Downtown Mall celebrates the ambience of the award-winning center city pedestrian mall of historic Charlottesville, Virginia. Includes thirty-six closely integrated short stories, a gallery of both contemporary and vintage photography, and a historical essay.

One of the most prolific and popular American writers of her time, Elizabeth Stuart Phelps is, nearly a century later, once more coming to be considered a major author. The Story of Avis, her most ambitious and successful novel, has long been out of print and will prove a revelation to modern readers. Avis is the story of a larger-than-life heroine, a promising artist, who against her better judgment is persuaded by her lover, Philip Ostrander--a "new man"--to marry. The failure of their modern marriage, and in due course of Avis's career, is inevitable. Phelps depicts the turmoil of her characters' inner lives with great sensitivity and with a skill that is striking. A feminist who clearly saw the constraints of traditional gender roles upon women and men, Elizabeth Stuart Phelps was ahead of her own time in post-Civil War America. She remains highly readable today. "The Story of Avis (1877) will shock any reader who still thinks nineteenth-century American women's fiction is sentimental and pious. This novel is angry, not sentimental; iconoclastic, not pious; it concerns a talented and dedicated painter whose marriage destroys her genius."--Choice "This ornately articulate novel is playful; both kind and hopeful in its vision of the female conundrum. . . . I had intended to speed read it]. I ready every word."--Joyce Bright, Belles Lettres