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To date, parasite diseases still affect millions of people
world-wide, mainly in developing countries. The recent sequencing
of parasite genomes opened a new era in parasitology research since
the acquisition of new genomic data, providing a useful tool to
analyse and compare gene structure, location and characteristics
from different species to study evolution and gene function. This
book is a collection of the recent findings of international
experts in modern parasitology, computational biology, evolutionary
biology, and genetics. It includes specific data on the current
knowledge and understanding of genome organisation, dynamic and
function for Plasmodium falciparum, Trypanosoma spp., Leishmania
spp., Trichomonas vaginalis, Giardia lamblia, Entamoeba histolytica
and Microsporidium, which represent the main causes of parasitic
infections in humans. This book will be an essential reference for
all parasitologists and scientists, as well as researchers,
postdoctoral fellows and graduate students in computational
biology, evolutionary biology, and genetics.
MicroRNA (miRNA) biology is a cutting-edge topic in basic as well
as biomedical research. This is a specialized book focusing on the
current understanding of the role of miRNAs in the development,
progression, invasion and metastasis of diverse types of cancer. It
also reviews their potential for applications in cancer diagnosis,
prognosis, and therapeutic targets. In addition it discusses the
potential use in translational medicine. Chapters in this book
present comprehensive and expert perspectives on the roles of
miRNAs in most common cancers from bench to bedside applications
and are written by an international team of renowned experts in the
field. This book is a landmark work providing up-to-date research
on miRNAs and their important roles in cancer translational
research.
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