This book is considered the first extended survey on algorithms and techniques for efficient cohesive subgraph computation. With rapid development of information technology, huge volumes of graph data are accumulated. An availability of rich graph data not only brings great opportunities for realizing big values of data to serve key applications, but also brings great challenges in computation. Using a consistent terminology, the book gives an excellent introduction to the models and algorithms for the problem of cohesive subgraph computation. The materials of this book are well organized from introductory content to more advanced topics while also providing well-designed source codes for most algorithms described in the book. This is a timely book for researchers who are interested in this topic and efficient data structure design for large sparse graph processing. It is also a guideline book for new researchers to get to know the area of cohesive subgraph computation.

This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology studies using model organisms are reviewed in detail. This is an ideal book for students and researchers in the microfluidics and molecular biology fields as well as engineers working in the biotechnology industry. This book also: Reviews exhaustively the latest techniques for single-cell genetic, epigenetic, metabolomic, and proteomic analysis Illustrates microfluidic approaches for inverse metabolic engineering, as well as analysis of circulating exosomes Broadens readers' understanding of microfluidics convection-based PCR technology, microfluidic RNA-seq, and microfluidics for robust mobile diagnostics

This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology studies using model organisms are reviewed in detail. This is an ideal book for students and researchers in the microfluidics and molecular biology fields as well as engineers working in the biotechnology industry. This book also: Reviews exhaustively the latest techniques for single-cell genetic, epigenetic, metabolomic, and proteomic analysis Illustrates microfluidic approaches for inverse metabolic engineering, as well as analysis of circulating exosomes Broadens readers' understanding of microfluidics convection-based PCR technology, microfluidic RNA-seq, and microfluidics for robust mobile diagnostics

It has become highly desirable to provide users with flexible ways to query/search information over databases as simple as keyword search like Google search. This book surveys the recent developments on keyword search over databases, and focuses on finding structural information among objects in a database using a set of keywords. Such structural information to be returned can be either trees or subgraphs representing how the objects, that contain the required keywords, are interconnected in a relational database or in an XML database. The structural keyword search is completely different from finding documents that contain all the user-given keywords. The former focuses on the interconnected object structures, whereas the latter focuses on the object content. The book is organized as follows. In Chapter 1, we highlight the main research issues on the structural keyword search in different contexts. In Chapter 2, we focus on supporting structural keyword search in a relational database management system using the SQL query language. We concentrate on how to generate a set of SQL queries that can find all the structural information among records in a relational database completely, and how to evaluate the generated set of SQL queries efficiently. In Chapter 3, we discuss graph algorithms for structural keyword search by treating an entire relational database as a large data graph. In Chapter 4, we discuss structural keyword search in a large tree-structured XML database. In Chapter 5, we highlight several interesting research issues regarding keyword search on databases. The book can be used as either an extended survey for people who are interested in the structural keyword search or a reference book for a postgraduate course on the related topics. Table of Contents: Introduction / Schema-Based Keyword Search on Relational Databases / Graph-Based Keyword Search / Keyword Search in XML Databases / Other Topics for Keyword Search on Databases