This book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.

This collection features five peer-reviewed reviews on rust diseases of cereals. The first chapter provides an overview of the wheat rust pathogen lifecycle that has been critical to the design of effective disease management strategies and discusses recent integration of basic biological knowledge and genomic-led tools within an epidemiological framework. The second chapter introduces stripe rust and provides an overview of its decimation of crop yields worldwide. The chapter summarises recent advances in identifying stripe rust resistance genes in wheat as a means of controlling disease spread and limiting its economic damage. The third chapter addresses the need for more effective and sustainable control of rust pathogens affecting wheat and barley in the face of increasing regulatory measures against the use of conventional fungicides, as well as the spread of fungicide resistance. The fourth chapter provides an overview of the recent advances in controlling wheat rust, focussing on the role of pathogen and host genetics, host-pathogen interactions, epidemiology and management strategies. The final chapter considers the main rust pathogens affecting sorghum and details the different conditions in which they proliferate, their symptoms and impact on crop yields.

"This book is number 106 in the Burleigh Dodds Series in Agriculture Science and continues this excellent series of informative reviews in plant and animal agricultural production systems. This volume is a collection of chapters by experts in cereal diseases and disease management from around the world and contains some excellent detailed overviews on recent advances in our understanding of key cereal pathogens and advances in their management. It will be a valuable resource for wheat and barley focussed researchers, breeders and growers." (Professor Matt Dickinson, University of Nottingham, UK - Plant Pathology) It's been estimated that up to 40% of crop yields are lost to pests and diseases worldwide, a problem exacerbated by increasing fungicide resistance. Given the continuous struggle between crops and the diseases which exploit them, achieving durable disease resistance remains a key challenge in ensuring global food security. A range of issues need to be addressed to meet this challenge for major diseases affecting cereal crops such as Fusarium, barley yellow dwarf virus (BYDV) and Septoria. Achieving durable disease resistance in cereals provides an authoritative review of key advances, from better understanding of pathogen biology/epidemiology and plant-pathogen interactions, to identifying sources of resistance and advances in techniques for breeding new varieties. This collection offers a comprehensive review of research on achieving durable resistance to diseases such as Fusarium head blight, Septoria tritici blotch, Septoria nodorum blotch, tan spot, blast, BYDV and Ramularia. Edited by Professor Richard Oliver, Curtin University, Australia, Achieving durable disease resistance in cereals will be an excellent reference for researchers in cereal science, arable farmers, government and private sector agencies supporting cereal production and companies supplying the cereals sector (e.g. seed companies). It complements Integrated disease management of wheat and barley, also edited by Professor Oliver, published by Burleigh Dodds Science in 2018.

This book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.

This book provides an up-to-date review of the fundamentals of sphingolipid metabolism and its role in metabolic diseases. Focusing on the sphingolipid de novo synthesis pathway, the effect of sphingomyelin, ceramide, and sphingosine-1-phosphate, and linkage between sphingolipids and other lipids, such as cholesterol, it covers serine palmitoyltransferase, ceramide synthases, ceramidases, sphingosine kinases, and sphingomyelin synthases, and more. While highlighting how rare diseases related to abnormal glycosphingolipid metabolism, this publication introduces sphingolipid metabolism-related diseases, such as lung diseases and cancers, as well as sphingolipid circadian regulation. The book demonstrates advances and limitations of research on sphingolipid metabolism and its roles in metabolic diseases and other diseases. It offers graduate students and researchers a coherent overview of sphingolipids, as well as the limitations of current research in the field, and promotes further studies on metabolic diseases, as well as pharmaceutical research on drug discovery based on sphingolipid de novo synthase.