Deploying lithium-ion (Li-ion) batteries depends on cost-effective electrode materials with high energy and power density to facilitate lower weight and volume. Si-based anode materials theoretically offer superior lithium storage capacity. Replacing a graphite anode with high-capacity materials such as silicon will further improve the energy density. Durable, low-cost, and high-energy-density materials are vital to developing plug-in electric vehicles as affordable and convenient as gasoline-powered ones, while reducing carbon emissions. This reference presents the knowledge gained over recent decades in the materials science and chemistry of silicon and its derivates as anode materials for Li-ion batteries, and provides insights into developing Si-based anode materials for next-generation batteries. Coverage includes the structure and chemistry of silicon, electrolytes and chemistry of Si anodes, nanostructure and binder additives for Si anodes, surface modification and mechanical properties. Researchers in academia and industry will find this detailed reference a highly useful resource.