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The last four decades of human history have seen the emergence of
an unprecedented number of 'new' infectious diseases: the familiar
roll call includes AIDS, Ebola, H5N1 influenza, hantavirus,
hepatitis E, Lassa fever, legionnaires' and Lyme diseases, Marburg
fever, Rift Valley fever, SARS, and West Nile. The outbreaks range
in scale from global pandemics that have brought death and misery
to millions, through to self-limiting outbreaks of mainly local
impact. Some outbreaks have erupted explosively but have already
faded away; some grumble along or continue to devastate as now
persistent features in the medical lexicon; in others, a huge
potential threat hangs uncertainly and worryingly in the air. Some
outbreaks are merely local, others are worldwide.
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