This unique Handbook charts shifts in the relationship between risks and inequalities over the last few decades, analysing how inequalities shape risk and how risks condition and intensify inequalities. Expert contributors examine the impacts of environmental, financial, social, urban, economic, and digital risks on inequalities, at both national and global levels. Identifying how the rise of novel risk formations is associated with changes in contemporary political economies, chapters explore new areas of research including the new urban crisis, the gendered impacts of precarious labour and social inequality in relation to agro-biotechnology. Contributing to an underdeveloped area of research, the Handbook breaks new ground to explore how tackling important issues via the prism of risk and inequality can provide novel insights, that solely focusing on only one or the other of these issues cannot. This Handbook will be critical reading for scholars and students of sociology, sociological theory, geography and political science. Its exploration of shifts in contemporary socially produced risks will also be beneficial for practitioners, economists and policy makers in these areas.