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This book highlights the role of nanotechnology concepts in the
management of COVID-19 pandemic. The book covers different aspects
of the causative agent SARS CoV2 (Severe Acute Respiratory Syndrome
Coronavirus-2) and the COVID-19 pandemic with a special emphasis on
nanotechnology. It discusses the origin and history of SARS CoV2
and the outbreak of COVID-19 and highlights the geographical
mutations in the SARS CoV2 virus genome, providing information
about the structural features, antigenicity and the life cycle of
SARS CoV2. The book provides an insight into
nanotechnology-virology interface and explains how nanomaterials
link the gap between the vital phases of SARS CoV2 life cycle and
the four modalities of COVID-19 management viz sensing/diagnosis,
therapy, prevention and self-protection. Further, the existing and
promising diagnostic tools for detection of COVID-19 are discussed
with an emphasis on nano PCR, nanoimmunosensors, biobarcode assay
and point of care approach and also describe the nanoparticles
involved in the CT imaging of lungs and SFHI (Spatial Frequency
Hetrodyne Imaging) for diagnosis of SARS COV2 infection. The book
concludes with details about translational medicine and explains
the types of SARS CoV2 vaccines, stages of COVID-19 vaccine
development and possible nanovaccines for COVID-19, followed by the
description on biopharmaceutical companies involved in the
production of SARS CoV2 vaccines.
This brief highlights nanoparticles used in the diagnosis and
treatment of prominent diseases and toxic conditions. Ecofriendly
methods which are ideal for the synthesis of medicinally valued
nanoparticles are explained and the characteristic features of
these particles projected. The role of these particles in the
therapeutic field, and the induced biological changes in some
diseases are discussed. The main focus is on inflammation,
oxidative stress and cellular membrane integrity alterations. The
effect of nanoparticles on these changes produced by various agents
are highlighted using in vitro and in vivo models. The mechanism of
nanoparticles in ameliorating the biological changes is supported
by relevant images and data. Finally, the brief demonstrates recent
developments on the use of nanoparticles in diagnosis or sensing of
some biological materials and biologically hazardous environmental
materials.
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Nadine Gordimer
Paperback
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R367
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