Now in a revised and updated second edition, this book encompasses the current knowledge of genetic and molecular causes of, and surgical and non-surgical treatment for, congenital deformities of the hand. Divided into five sections, this comprehensive text presents the many variations of congenital anomaly encountered in the clinical setting. Part I discusses general considerations for congenital deformity, including embryology and classification, incidence and prevalence, genetics, anesthesia, prosthetics and rehabilitation principles, hand therapy and even psychological considerations for children living with these conditions. The second and third sections present deformities based on failures of formation and/or differentiation of the axis and hand plate respectively: radial and ulnar longitudinal deficiencies, symbrachydactyly, syndactyly (including Apert Syndrome), clinodactyly and captodactyly, and synostosis and coalitions are described in detail, among others. Duplication deformities, such as radial and ulnar polydactyly, are covered in part IV. The final section discussed overgrowth (macrodactyly), amniotic band syndrome, arthrogryposis, Madelung deformity, epidermolysis bullosa and additional generalized skeletal anomalies. All chapters are generously referenced and illustrated with radiography and full-color photographs. Bringing together the latest clinical evidence and surgical interventions, this second edition of Congenital Anomalies of the Upper Extremity will continue to be an excellent resource for orthopedic, hand and plastic surgeons treating young patients with these challenging deformities of the hand.

The original intermittent fasting diet - now up-dated and expanded
An easy-to-follow, safe, and science-based alternate-day calorie-restriction program that promotes weight loss and longevity, The Alternate-Day Diet includes the most up-to-date research on calorie restriction and intermittent fasting as well as additional techniques (including supplementation and eating according to the body's natural circadian rhythms) to enhance the diet's effectiveness.
The Alternate-Day Diet describes how limiting caloric intake every other day can activate a gene called SIRT1 which reduces inflammation, lowers free radical stress, improves insulin resistance, and most important, causes fat loss by releasing fat cells from around the organs. In short, activating SIRT1 promotes weight loss and longevity.
The simple two-step program calls for you to limit calories one day and eat normally the next and the book outlines lifestyle suggestions to support the diet's effectiveness including proper hydration and exercise, which are also key components to maximizing weight-loss.
Throughout, you will be inspired by the anecdotes and testimonials from real people who have used the diet successfully to lose weight, and to find relief from a range of health issues including heart disease, Type II diabetes, autoimmune diseases, and even menopause-related hot flashes.