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The gastrointestinal tract has a number of unique features. Its
extensive surface is formed by a single layer of rapidly renewing
cells, the intestinal epithelial cells. These cells are in contact
with a number of other cell populations, including the largest part
of the immune system, and with an excessive luminal antigen load,
including vast numbers of bacteria. Furthermore two more organs,
namely liver and pancreas, are part of the system. The rapid
renewal of the epithelial layer, the interactions of different cell
types, and the balance between cell proliferation and death, have
been fascinating subjects of studies in recent years. Much has been
learned, and cytokines have emerged as important mediators for all
these interactions and homeostatic systems. This book, the
proceedings of the Falk Symposium 113 on `Cytokines and Cell
Homeostasis in the Gastrointestinal Tract', held in Regensburg,
Germany, 16-18 September 1999, provides a forum for basic
scientists and interested clinicians to exchange ideas, to discuss
concepts and to plan further studies.
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