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The Handbook of Metabolic Phenotyping is the definitive work on the
rapidly developing subject of metabolic phenotyping. It explores in
detail the wide array of analytical chemistry and statistical
modeling techniques used in the field, coupled with surveys of the
various application areas in human development, nutrition, disease,
therapy, and epidemiology to create a comprehensive exploration of
the area of study. It covers recent studies that integrate the
various -omics data sets to derive a systems biology view. It also
addresses current issues on standardization, assay and statistics
validation, and data storage and sharing. Written by experts with
many years of practice in the field who pioneered many of the
approaches widely used today, The Handbook of Metabolic Phenotyping
is a valuable resource for postgrads and research scientists
studying and furthering the field of metabolomics.
Molecular biology operates at three levels - genes, proteins and
metabolites. This book is unique in that it provides a
comprehensive description of an approach (metabonomics) to
characterise the endogenous metabolites in a living system,
complementing gene and protein studies (genomics and proteomics).
These "omics" methods form the basis for understanding biology at a
systems level.
The Handbook of Metabonomics and Metabolomics aims to be the
definitive work on the rapidly expanding subjects of metabolic
profiling, metabolite and biomarker identification, encompassing
the fields of metabonomics and metabolomics. It covers the
principles of the subject, the analytical and statistical
techniques used and the wide variety of applications.
* comprehensive description of an approach (metabonomics) to
characterise the endogenous metabolites in a living system,
complementing gene and protein studies
* aims to be the definitive work on the rapidly expanding subjects
of metabolic profiling, metabolite and biomarker
identification
* covers the principles of the subject, the analytical and
statistical techniques used and the wide variety of applications.
Metabolic Phenotyping in Personalized and Public Healthcare
provides information on the widespread recognition that a
personalized or stratified approach to patient treatment may offer
a more efficient and effective healthcare solution than
phenotype-led approaches. In order to achieve that objective, a
deep personal description is required at the level of the genome,
proteome, metabolome, or preferably a combination of these aided by
technology. This book, edited and written by the outstanding
luminaries of this evolving field, evaluates metabolic profiling
and its uses across personalized and population healthcare, while
also covering the advent of new technology fields, such as surgical
metabonomics. In addition, the text presents specific examples of
where this technology has been used clinically and with efficacy,
pointing towards a framework and protocol for usage as it hits the
clinical mainstream.
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