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In 1898 Camillo Golgi reported his newly observed intracellular
structure, the apparato reticolare interno, now universally known
as the Golgi Apparatus. The method he used was an ingenious
histological technique (La reazione nera) which brought him fame
for the discovery of neuronal networks and culminated in the award
of the Nobel Prize for Physiology and Medicine in 1906. This
technique, however, was not easily reproducible and led to a
long-lasting controversy about the reality of the Golgi apparatus.
Its identification as a ubiquitous organelle by electron microscopy
turned out to be the breakthrough and incited an enormous wave of
interest in this organelle at the end of the sixties. In recent
years immunochemical techniques and molecular cloning approaches
opened up new avenues and led to an ongoing resurgence of interest.
The role of the Golgi apparatus in modifying, broadening and
refining the structural information conferred by
transcription/translation is now generally accepted but still
incompletely understood. During the coming years, this topic
certainly will remain center stage in the field of cell biology.
The centennial of the discovery of this fascinating organelle
prompted us to edit a new comprehensive book on the Golgi apparatus
whose complexity necessitated the contributions of leading
specialists in this field. This book is aimed at a broad readership
of glycobiologists as well as cell and molecular biologists and may
also be interesting for advanced students of biology and life
sciences.
'Just read it.' Elon Musk The dramatic inside story of the first
four historic flights that launched SpaceX-and Elon Musk-from a
shaky startup into the world's leading edge rocket company. SpaceX
has enjoyed a miraculous decade. Less than 20 years after its
founding, it boasts the largest constellation of commercial
satellites in orbit, has pioneered reusable rockets, and in 2020
became the first private company to launch human beings into orbit.
Half a century after the space race SpaceX is pushing forward into
the cosmos, laying the foundation for our exploration of other
worlds. But before it became one of the most powerful players in
the aerospace industry, SpaceX was a fledgling startup, scrambling
to develop a single workable rocket before the money ran dry. The
engineering challenge was immense; numerous other private companies
had failed similar attempts. And even if SpaceX succeeded, they
would then have to compete for government contracts with titans
such as Lockheed Martin and Boeing, who had tens of thousands of
employees and tens of billions of dollars in annual revenue. SpaceX
had fewer than 200 employees and the relative pittance of $100
million in the bank. In Liftoff, Eric Berger takes readers inside
the wild early days that made SpaceX. Focusing on the company's
first four launches of the Falcon 1 rocket, he charts the bumpy
journey from scrappy underdog to aerospace pioneer. drawing upon
exclusive interviews with dozens of former and current engineers,
designers, mechanics, and executives, including Elon Musk. The
enigmatic Musk, who founded the company with the dream of one day
settling Mars, is the fuel that propels the book, with his daring
vision for the future of space.
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