Morphology.- The Pineal Gland of Mammals: Some Open Morphological Questions.- Demonstration of Nerve Fibers Immunoreactive to met-Enkephalin, leu-Enkephalin, and ss-Endorphin in the Bovine Pineal Gland.- Comparative Studies of VIP-, PHI-, and NPY-Immunoreactive Nerve Fibers in the Pineal Gland of the Sheep.- Biochemistry.- Pharmacological Regulation of Receptor-Mediated Indoleamine Metabolism in the Mammalian Pineal Gland.- Regulation of Melatonin Synthesis and Release: Paracrine Relationships in Mammalian Pineal Gland.- New Aspects Concerning the Regulation of Pineal Indoleamine Metabolism: Implications for Neuroimmunology.- The Use of Perifusion Technique in the Research of Pineal Neuroendocrinology. The Role of Different Neurotransmitters in the Regulation of Pineal Melatonin Secretion.- Interferon-? Modulates Indoleamine Metabolism in Rat Pineal Gland in Organ Culture.- Melatonin Receptors.- High-affinity Melatonin Receptors in Mammals: Localization, G-Protein Coupling and Signal Transduction.- Melatonin Receptors in Discrete Areas of Rat and Hamster Brain: Modulation by Melatonin, Testosterone and the Photoperiod.- Melatonin Binding Sites in the Nervous and Immune Systems.- 2-?125I? Iodomelatonin Binding in Normal and Neoplastic Tissues.- Melatonin in the gastrointestinal tract.- Biochemical Characteristics of Melatonin Receptors in Different Organs and Translation of Hormonal Signal in the Nucleus.- Physiology.- Annual Changes in the Daily Pattern of Melatonin Synthesis and Release.- Integration of Environmental Signals by the Pineal Gland and its Significance for Seasonality in Small Mammals.- Opioid Involvement in Melatonin Action.- Effect of Melatonin on NADH-Oxidoreductase Activity and Cyclic Nucleotide Levels in Rat Adrenals.- Temporal Profile of Superoxide Dismutase Activity in the Pineal Gland and the Liver of Rats.- Pineal-Harderian Gland Interactions: Morphological and Physiological Evidences for an Endocrine Function of the Syrian Hamster Harderian Gland.- Melatonin Enhances GABA-Mediated Effects when Administered by Micropressure Ejection in Single Unit Neuronal Recordings.- Immunology.- Action of Melatonin on Immune System.- Opioids in Immune Cells.- Spleen Morphology and Lymphoproliferative Activity in Short Photoperiod Exposed Hamsters.- Melatonin Reconstitutes the Decreased CFU-S Content in the Bone Marrow of Hypothalamus - Lesioned Mice.- Oncology.- Melatonin Action on Oncogenesis.- The Effects of Melatonin and Melatonin Analogues on the P388, DLD-1 and MCF-7 Tumor Cell Lines.- Is there a Role for the Pineal Gland in Neoplastic Growth?.- Clinical Studies.- Melatonin, Immunity and Cancer in Humans.- Evidence for a Sex-Specific Facilitatory Effect of Melatonin on Prolactin Secretion. Is Pineal-Prolactin Interaction Relevant to the Clinical Course of Breast Cancer?.- Pineal-Interleukin 2 Interactions and their Possible Importance in the Pathogenesis of Immune Dysfunctions in Cancer.- Significance of Melatonin to Chronobiology: Immunological Correlations.- Circadian Profile of Serum Melatonin in Cushing's Syndrome and Acromegaly.- Urinary 6-Sulfatoxymelatonin Excretion in Breast Cancer Patients and Control Subjects.- Interindividuel Differences in the Responses of Serum and Salivary Melatonin to Light.- Contributors.

Pineal Gland Regulation: Expression of Neurotransmitter Receptor Subtypes and Subunits in the Mammalian Pineal Gland; M. Moller, et al. Transcription Factor Icer and Regulation of Rat Photoneuroendocrine System; J.H. Stehle. Intracellular Actions of Melatonin with a Summary of Its Interactions with Reactive Oxygen Species; R.J. Reiter. Melatonin Receptors: Brain Melatonin Receptors: Distribution and Physiological Significance; B. Stankov, F. Fraschini. Localization and Physiological Role of Melatonin Receptors in the Visual and Circadian Systems; M.L. Dubocovick, et al. Melatonin Receptors in Brain and Peripheral Arteries; M. Viswanathan, et al. Melatonin in the Circadian System: The Role of the Circadian System in Photoperiodic Time Measurement in Mammals; M.H. Hastings, et al. Melatonin and the Vertebrate Circadian System: Pharmacological Effects; J.R. Redman. Melatonin Analogs: New Molecules Active at the Melatonin Receptor Level; F. Fraschini, B. Stankov. Development of Melatonin Analogs; P. Delagrange, et al. Melatonin in Humans: Significance of Melatonin in Humans; J. Arendt. The Influence of Melatonin on the Human Circadian Clock; A.J. Lewy, et al. 8 additional articles. Index.