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This second edition provides a sound basis for the molecular
investigation of NLR function in health and disease. Chapters focus
on NLR as innate immune receptors, “atypical†inflammasomes,
biochemical and novel bioluminescence techniques for the
measurement of IL-1b as readout of NLR-based inflammasomes,
bioluminescent probe, biochemical and microscopy techniques,
techniques to measure caspase-1 activation, cell free systems for
the study of inflammasome function, and inflammasome activation.
Written in the highly successful Methods in Molecular Biology
series format, chapters include introductions to their respective
topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and key
tips on troubleshooting and avoiding known pitfalls.Â
Authoritative and cutting-edge, NLR Proteins: Methods and
Protocols, Second Edition aims to be a useful and practical guide
to new researcher sand experts looking to expand their
knowledge.Â
This volume provides a sound basis for the molecular investigation
of NLR function in health and disease. Chapters focus on of innate
immune receptors, "atypical" inflammasomes, biochemical and novel
bioluminescence techniques for the measurement of IL-1b,
bioluminescent probe, biochemical and microscopy techniques,
techniques to measure caspase-1 activation, cell free systems for
the study of inflammasome function, and inflammasome activation.
Written in the highly successful Methods in Molecular Biology
series format, chapters include introductions to their respective
topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Authoritative and
cutting-edge, NLR Proteins: Methods and Protocols aims to ensure
successful results in the further study of this vital field.
This volume provides a sound basis for the molecular investigation
of NLR function in health and disease. Chapters focus on of innate
immune receptors, "atypical" inflammasomes, biochemical and novel
bioluminescence techniques for the measurement of IL-1b,
bioluminescent probe, biochemical and microscopy techniques,
techniques to measure caspase-1 activation, cell free systems for
the study of inflammasome function, and inflammasome activation.
Written in the highly successful Methods in Molecular Biology
series format, chapters include introductions to their respective
topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Authoritative and
cutting-edge, NLR Proteins: Methods and Protocols aims to ensure
successful results in the further study of this vital field.
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