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Very small particles are able to show astonishing properties. For
example, gold atoms can be combined like strings of pearls, while
nanoparticles can form one-, two- and three-dimensional layers.
These assemblies can be used, for instance, as semiconductors, but
other electronic as well as optical properties are possible.
An introduction to the booming field of "nanoworld" or
"nanoscience," from fundamental principles to their use in novel
applications.
With its clear structure and comprehensive coverage, backed by
numerous examples from recent literature, this is a prime reference
for chemists and materials scientists working with and developing
nanoparticle systems.
A bestselling title in its second edition. A must-have reference
for chemists and materials scientists.
Many compounds of biological and pharmacological interest are as-
metric and show optical activity. Approximately 40% of the drugs in
use are known to be chiral and only about 25% are administered as
pure enantiomers. It is well established that the pharmacological
activity is mostly restricted to one of the enantiomers (eutomer).
In several cases, unwanted side effects or even toxic effects may
occur with the inactive enantiomer (distomer). Even if the side
effects are not that drastic, the inactive enantiomer has to be
meta- lized, which represents an unnecessary burden for the
organism. The admin- tration of pure, pharmacologically active
enantiomers is therefore of great importance. The ideal way to get
to pure enantiomers would be by enantioselective synthesis.
However, this approach is usually expensive and not often
practicable. Usually, the racemates are obtained in a synthesis,
and the separation of the enantiomers on a preparative scale is
necessary. On the other hand, there is also a great demand for
methods of enantiomer separation on an analytical scale for
controlling synthesis, checking for racemization p- cesses,
controlling enantiomeric purity, and for pharmacokinetic studies.
C- ventional methods for enantiomer separation on a preparative
scale are fractionated crystallization, the formation of
diastereomeric pairs followed by repeated recrystallization, and
enzymatic procedures. In recent years, ch- matographic methods such
as gas chromatography and, especially, liquid ch- matography have
attracted increasing interest for chiral separation, both on
analytical and preparative scales.
The ultimate reference book, providing an in-depth introduction to
nanotechnology, discussing topics from ethics and philosophy to
challenges faced by this up-and-coming industry, all in one
comprehensive volume. The topic could not be hotter, Nanotechnology
is the new technology drive of the 21st century paired with
existing, multibillion dollar markets and fundings.
The entire reference set of 9 volumes gives an excellent,
in-depth overview of everything you need to know about
nanotechnology and nanoscience with each volume dedicated to a
specific topic which is covered in detail by experts from that
particular field.
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