The birth of Louise Joy Brown - the world's first baby born following in-vitro fertilization - heralded a medical revolution. Forty years later, many thousands of babies are born each year following IVF. Assisted reproduction is a global industry with a multi-billion dollar turnover. It is a complex mix of science, clinical management, bioethics, and commercial imperatives. Many of the pioneers of IVF are still with us and have a fascinating tale to tell. Here, they relate the story of the development of IVF and related technologies in a way that will prove invaluable to future generations of practitioners seeking to understand the genesis of the specialty. This is not an academic history: rather it takes an informal and anecdotal approach; informing and entertaining for generations of past, present and future medical and scientific specialists of IVF, alongside the millions of parents, who celebrated the successes of IVF treatment worldwide.

This book is a comparative analysis of the value orientations of Buddhist and Christian entrepreneurs and how these values impact business. The chapters review and analyze the concepts of Buddhist economics and the social teaching of the Roman Catholic Church. The value orientations of Buddhist and Christian entrepreneurs are described by irreducible core values that correspond to the ontological conception, the procedural dimension, and the "other directedness" of a spiritual value commitment in business. The book includes the reflections of Buddhist and Christian entrepreneurs about business spirituality, profit, the temporal perspectives of business, and stakeholder management. The cases testify that a spiritual value orientation can contribute to creating genuine ethical commitment. The findings and the examples can encourage business scholars and practitioners to stop considering ethics as an instrument in the service of profit and serve as inspiration for integrating spirituality into business in a profound way. This book will be of interest to scholars studying business ethics, workplace spirituality and faith at work.

This book is a comparative analysis of the value orientations of Buddhist and Christian entrepreneurs and how these values impact business. The chapters review and analyze the concepts of Buddhist economics and the social teaching of the Roman Catholic Church. The value orientations of Buddhist and Christian entrepreneurs are described by irreducible core values that correspond to the ontological conception, the procedural dimension, and the "other directedness" of a spiritual value commitment in business. The book includes the reflections of Buddhist and Christian entrepreneurs about business spirituality, profit, the temporal perspectives of business, and stakeholder management. The cases testify that a spiritual value orientation can contribute to creating genuine ethical commitment. The findings and the examples can encourage business scholars and practitioners to stop considering ethics as an instrument in the service of profit and serve as inspiration for integrating spirituality into business in a profound way. This book will be of interest to scholars studying business ethics, workplace spirituality and faith at work.

The last step in the IVF treatment cycle, embryo transfer, is also the process with the highest failure rate. No matter how good the laboratory technique is, a successful pregnancy will not be achieved without meticulous preparation of the uterus to accept the embryo. This book reviews the scientific evidence on endometrial receptivity, including histological, hormonal, biochemical, and immunological factors. Practical and concise, it supports gynecologists and embryologists to make evidence-based decisions that can influence the success rates of implantation and live births. Part of a series of books offering treatments and strategies for fertility and conception to optimize IVF outcomes, this volume is for all clinicians and embryologists working in reproductive medicine.

Planned parenthood - and its associated reproductive and sexual healthcare issues - has massive socioeconomic and demographic consequences worldwide. Modern contraception played a major role in the emancipation of women and has huge potential for a sustainable future world population. Yet it is a medical topic which always raises controversy, with serious ethical, religious and cultural overtones. This is an authoritative guide for all those working in reproductive healthcare. Highly practical, evidence-based, with enough detail to inform effective clinical practice, the book is structured on a lifestage approach, mirroring everyday experience of practitioners. All forms of contraceptives are covered in detail, with guidance on prescribing, the advantages and disadvantages of various techniques, and possible complications. The wider field of reproductive healthcare including subfertility and sexual assault are also covered. An ideal guide to contraception for trainees in obstetrics and gynaecology, primary care physicians and nurse-practitioners.

This comprehensive review of the factors that affect the harvesting and preparation of oocytes and the management of embryos will allow practitioners to make evidence-based decisions for successful IVF. The book reviews and re-considers the value of strategies and outcomes in the management of fertility and conception rates, centred on the production of oocytes, and successful development of the embryo. Authored by leading experts in the field, chapters engage with treatments and strategies that affect the production of oocytes and embryos, optimizing outcomes in the management of female fertility, conception rates, and live births. This vital guide covers controlled ovarian hyperstimulation, the role of AMH in determining ovarian reserve, and primary stimulation agents and the use of adjuncts. Integral for all clinicians and embryologists working in reproductive medicine units, readers are provided with evidence-based, comprehensive advice and review of all factors affecting the management of oocytes and the embryo that are vital for successful IVF cycles.

Male factor infertility is receiving greater emphasis in IVF programs. This book reviews the scientific evidence for various medical, environmental and lifestyle factors that can affect male fertility, such as chromosome abnormalities, age, anti-sperm antibodies and endocrine disruptors. Part of a four-book series on improving IVF success, this volume subsequently explores a range of treatments and strategies to improve sperm quality, including FSH treatment and antioxidants. It also discusses methods to prevent male infertility from childhood through to adulthood. Concise, practical and evidence-based - and with insights from global experts in the field - this text will enable gynecologists, urologists and andrologists to make evidence-based decisions that can influence the success rate of fertilization in subsequent IVF cycles.

In addition to covering clinical topics and surgical procedures, this essential textbook provides detailed commentary on the contemporary social, psychological and economic issues that affect women's health. Acknowledged authorities in respective research fields have contributed specific sections to address the topics of women's mental health, genetics, prescribing for women, health promotion, hormones throughout the life cycle, psychological and behavioral issues.

The birth of Louise Joy Brown - the world's first baby born following in-vitro fertilization - heralded a medical revolution. Forty years later, many thousands of babies are born each year following IVF. Assisted reproduction is a global industry with a multi-billion dollar turnover. It is a complex mix of science, clinical management, bioethics, and commercial imperatives. Many of the pioneers of IVF are still with us and have a fascinating tale to tell. Here, they relate the story of the development of IVF and related technologies in a way that will prove invaluable to future generations of practitioners seeking to understand the genesis of the specialty. This is not an academic history: rather it takes an informal and anecdotal approach; informing and entertaining for generations of past, present and future medical and scientific specialists of IVF, alongside the millions of parents, who celebrated the successes of IVF treatment worldwide.

Several studies have looked at populations of volunteers, women from the electoral roll and women attending general practices, and have reported the ultrasound appearance of polycystic ovaries in as many as one in three to one in five. If groups of women with irregular periods are looked at, up to 90% will have polycystic ovaries at ultrasound. Similarly, when women with increased facial and body hair are screened, about 90% will have polycystic ovaries, as will three out of four women with acne. It has also been suggested by some studies that women with recurrent miscarriage or early pregnancy loss after in-vitro fertilisation have an increased incidence of polycystic ovaries. However, not all studies support this hypothesis, and additional research is needed to evaluate this further. This book looks at the historical background of this condition; the structure and function of the female genital organs; symptoms and signs; diagnostic techniques; the inheritance of polycystic ovary syndrome; long-term effects; lifestyle factors; polycystic ovaries and the skin; ovulation induction; surgical treatment to induce ovulation; in-vitro fertilisation; pregnancy outcomes.

This book constitutes the proceedings of the 18th International System Design Language Forum, SDL 2017, held in Budapest, Hungary, in October 2017. The 10 full papers presented in this volume were carefully reviewed and selected from 17 submissions. The selected papers cover a wide spectrum of topics related to system design languages ranging from the system design language usage to UML and GRL models; model-driven engineering of database queries; network service design and regression testing; and modeling for Internet of Things (IoT) data processing.

Greenfield's is the world’s leading neuropathology reference. It provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The two volume work provides a remarkable text which is clear, comprehensive and precise with exceptional illustrations. The tenth edition features fully updated sections covering CNS tumours, neurodegeneration, skeletal muscle, epilepsy, paediatric and forensic neuropathology.Expert coverage from an international team of Editors and contributors ensures authoritative and up to date content. The two volume set includes a downloadable and easily used e-version. This is a tried and tested reference for scientists, clinicians, researchers, and students who wish to learn more about neurological disease.