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This historic book may have numerous typos and missing text.
Purchasers can download a free scanned copy of the original book
(without typos) from the publisher. Not indexed. Not
illustrated.1916 Excerpt: ... five minutes is allowed for the
passage of the Salvarsan into the vein, and the rate of flow is
regulated by the height of the receptacle. This operation requires
strict asepsis at every step. Dose. Speaking of the use of
Salvarsan in syphilis, Ehrlich says: "The dose depends entirely on
the type and stage of the disease." Ordinarily, fr. 0.1 to 0.6 gm.
is used at intervals of from 5 to 10 days. In rare instances
smaller or larger doses may be tried. Caution. When danger is to be
feared begin treatment with a series of very small doses at long
intervals, or an energetic course of Mercury. The combined use of
large doses of Salvarsan and of Mercury at the same time is
believed to be unsafe. Note.--Alternate courses of Salvarsan and of
Mercury are to be recommended for syphilis. NEOSALVARSAN. Action.
Like that of Salvarsan but less powerful in equal dosage. Toxic
Effects. Similar to those of Salvarsan but milder with equal
dosage. Indications. In may be preferred to Salvarsan because
easier to prepare, or when toxic effects are feared.
Contraindications. As for Salvarsan. Administration. Use
immediately, because contact with air causes rapid decomposition.
Do not mix the drug until everything is prepared and the needle
already in the vein. Dose. 0.9 gm. of Neosalvarsan contains the
same quantity of arsenic as 0.6 gm. Salvarsan. Preparation of
Alkaline Solution of Salvarsan for Intravenous Use. Printed
instructions for preparing the solution are provided with the drug.
Technic of the Massachusetts General Hospital. 1. Everything used
for preparing the solution is sterilized beforehand, and is handled
under strictly aseptic precautions. The full dose of 0.6 gm. is
being used less frequently, and smaller doses more frequently now
at the Mass. Gen. Hosp. 2. The ...
Additional Contributors Are Jack H. Sandground And Samuel Drury
Clark.
Additional Contributors Are Jack H. Sandground And Samuel Drury
Clark.
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