In this issue of Psychiatric Clinics, guest editors Drs. Louis J. Marino, Jr. and George Zubenko bring their considerable expertise to the topic of Geriatric Psychiatry. Top experts in the field cover key topics such as insomnia and sleep disorders in older adults; substance use disorders in the elderly; comorbidity and management of concurrent psychiatric and medical disorders; mood disorders in the elderly; cognitive impairment in the elderly; and more. Contains 13 relevant, practice-oriented topics including psychopharmacology in the elderly: why does age matter?; the impact of SARS-CoV-2 infection and pandemic on mental health and brain function in the elderly; COVID-19: brain effects; epidemiology of psychiatric illness in the elderly; and more. Provides in-depth clinical reviews on current topics in geriatric psychiatry, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.