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Accessible and user-friendly, Cell Biology, 4th Edition, provides a
strong foundation for students entering health care career paths as
well as higher level research areas. Clear, readable text and
high-quality, detailed illustrations help readers quickly grasp
challenging content-all focusing on cellular processes without
delving into molecular processes. Drs. Thomas D. Pollard, William
C. Earnshaw, Jennifer Lippincott-Schwartz, and author/illustrator
Dr. Graham Johnson have thoroughly updated this popular text to
ensure its relevance for students in biology, biotechnology,
medicine, and pathophysiology, covering key principles of cellular
function and explaining how molecular defects lead to cellular
dysfunction and cause human disease. Clear, readable explanations
provide a concise story about how cells function at the molecular
level. An intuitive chapter flow starts with genome organization,
gene expression, and RNA processing as a foundation for
understanding every aspect of cellular function and physiology.
Brings cellular biology to life for students interested in medical
science by explaining how mutations in genes can compromise
virtually every cellular system and predispose to human disease.
Knowledge of cell biology has led to new treatments for cancer,
heart failure, cystic fibrosis, and many other diseases. Unique
illustrations with realistic proportions and relationships explain
every cellular process including the assembly of SARS CoV-2, the
structures attaching mitotic chromosomes to microtubules, the
mechanism of DNA replication and how pumps, carriers and channels
orchestrate physiological processes from synaptic transmission to
cellular volume regulation. Covers exciting breakthroughs such as
SMC motor proteins actively organizing chromosomal DNA, TOR kinases
regulating metabolism, new types of immunotherapy for cancer
treatment, mechanisms regulating fast axonal transport and their
relation to neurodegenerative diseases, how completion of DNA
replication sets the time for cells to enter mitosis, how a cascade
of signals specifies the site of cell division, and newly
understood pathways of normal and pathological cell death. Enhanced
eBook version included with purchase. Your enhanced eBook allows
you to access all of the text, figures, and references from the
book on a variety of devices.
Francis Poulenc (1899-1963) is widely acknowledged as one of the
twentieth century's most significant masters of vocal music-solo,
choral and operatic-quite apart from his achievements in
instrumental spheres. But what it cost him has been underestimated.
In this seminal biography, which will serve as the definitive guide
to the songs, Graham Johnson shows that it is in Poulenc's
extraordinary songs and seeing how they fit into his life-his
hidden sexuality, addiction and all-that we discover the composer's
essential artistic being. With Jeremy Sams's song translations, the
first in over forty years, and the insight that comes from a
lifetime of performing this music, Johnson provides an essential
volume for singers, pianists, listeners and readers interested in
the artistic milieu of modernism in the first half of the twentieth
century.
This collection of eight 'lectures' by internationally acclaimed
pianist, Graham Johnson, is based on a series of concert talks
given at the Guildhall School of Music and Drama as part of the
Benjamin Britten festival in 2001. The focus of the book is on
Britten's songs, starting with his earliest compositions in the
genre. Graham Johnson suggests that the nature of Britten's
creativity is especially apparent in his setting of poetry, that he
becomes the poet's alter-ego. A chapter on Britten's settings of
Auden and Eliot explores the particular influences these writers
brought to bear at opposite poles of the composer's life. The
inspiration of fellow musicians is also discussed, with a chapter
devoted to Britten's time in Russia and his friendship with the
Rostropovitch family. Closer to home, the book places in context
Britten's folksong settings, illustrating how he subverted the
English folksong tradition by refusing to accept previous
definitions of what constituted national loyalty. Drawing on
letters and diaries, and featuring a number of previously
unpublished photographs, this book illuminates aspects of Britten's
songs from the personal perspective of the pianist who worked
closely with Peter Pears after Benjamin Britten was unable to
perform through illness. Johnson worked with Pears on learning the
role of Aschenbach in 'Death in Venice' and was official pianist
for the first master class given by Peter Pears at Snape in 1972.
This collection of imagined book covers will have you scratching
your head and laughing out loud with every page turn. Though Pranks
with Sausages and Holy Bible II don't actually exist, Rejected
Books offers up a professionally produced catalogue of the worst
books imaginable, and what these tomes (and plenty more) could look
like. Rejected Books includes delightfully weird covers of imagined
books like: The Sculptors Who Couldn't Do Hands Cooking with Breast
Milk Possessed Toys: A Buying Guide Unfortunate Gluing Accidents
Camel Toes Through History Enjoy the worst book pitches of all time
and rest assured that anyone can have a future in publishing ...
even if your ideas are totally horrible.
The career of Gabriel Faure as a composer of songs for voice and
piano traverses six decades (1862-1921); almost the whole history
of French melodie is contained within these parameters. In the
1860s Faure, the lifelong protege of Camille Saint-SaA"ns, was a
suavely precocious student; he was part of Pauline Viardot's circle
in the 1870s and he nearly married her daughter. Pointed in the
direction of symbolist poetry by Robert de Montesquiou in 1886,
Faure was the favoured composer from the early 1890s of Winnarretta
Singer, later Princesse de Polignac, and his songs were revered by
Marcel Proust. In 1905 he became director of the Paris
Conservatoire, and he composed his most profound music in old age.
His existence, steadily productive and outwardly imperturbable, was
undermined by self-doubt, an unhappy marriage and a tragic loss of
hearing. In this detailed study Graham Johnson places the vocal
music within twin contexts: Faure's own life story, and the
parallel lives of his many poets. We encounter such giants as
Charles Baudelaire and Paul Verlaine, the patrician Leconte de
Lisle, the forgotten Armand Silvestre and the Belgian symbolist
Charles Van Lerberghe. The chronological range of the narrative
encompasses Faure's first poet, Victor Hugo, who railed against
Napoleon III in the 1850s, and the last, Jean de La Ville de
Mirmont, killed in action in the First World War. In this
comprehensive and richly illustrated study each of Faure's 109
songs receives a separate commentary. Additional chapters for the
student singer and serious music lover discuss interpretation and
performance in both aesthetical and practical terms. Richard Stokes
provides parallel English translations of the original French
texts. In the twenty-first century musical modernity is evaluated
differently from the way it was assessed thirty years ago. Faure is
no longer merely a 'Master of Charms' circumscribed by the belle
epoque. His status as a great composer of timeless
It was a brutal murder, and the trial of the decade. On 1 November
2007, 21-year-old British student Meredith Kercher was slaughtered
in cold blood in the apartment in Perugia, Italy, that she shared
with three other girls. Two bright young people, Amanda Knox and
her Italian ex-boyfriend, Raffaele Sollecito, stood accused of the
killing in a trial that lasted through 2009. They were found guilty
and sentenced to twenty-six and twenty-five years respectively on 4
December. A second man, Ivory Coast-born Rudy Guede, 22, had
already been found guilty of the sexual assault and murder of
Meredith in a separate trial in 2008 and sentenced to thirty years,
but the prosecution always stated that he didn't act alone. Kercher
was a model student whilst American Knox acquired a reputation that
fuelled specualtion about her character. Her bizarre behaviour just
after Meredith's body was found, her false accusation of an
innocent man, her weak alibi and her DNA on the murder weapon - a
kitchen knife found to be scubbed with bleach - went against her.
TV producer Paul Russell and critically acclaimed crime writer
Graham Johnson have teamed up with leading Italian forensics expert
General Luciano Garofano to reveal the full truth behind this
sensational murder and its trial. They unravel all the details and
study all the personalities in this case that has stunned the
world. Complex, and some say controversial, DNA evidence is
explained in simple language and, bit by bit, a story emerges of
brutality and jealousy in a university town where all was not what
it seemed. Their findings make for gripping, sensational reading.
A unique record of Poulenc (1899-1963) who is considered the
greatest composer of melodies of his period, a period that opened
with the aftermath of the First World War and closed as recently as
1960. He set to music poetry by all the greatest French twentieth
century poets as well as others from earlier times. He wrote this
diary of songs as an answer to what he felt were the frequent
misinterpretations of his work. It describes the origins of each
song, comments on performances he heard and offers guidelines for
interpretation. The diary is filled out with explanatory notes, a
collection of unfamiliar photographs and the English translation to
the text written opposite the French original. It will appeal to
singers who include French song in his or her repertoire and also
to those who have an interest in music of this period. The
translator, Winifred Radford is also the singer who gave the first
performance in England of Poulenc's song cycle Fiancailles pour
rire in 1945. She was coached by Poulenc and Pierre Bernac with
whom she later translated The Interpretation of French Song and
Francis Poulenc - The Man and his Songs.
'The young bloods did not care whether they killed criminals or
civilians . . .' The Cartel is Britain's biggest drugs gang, a
global corporation employing thousands of criminals and flooding
Britain with cocaine and heroin. Yet the established order is under
threat: street gangs are overwhelming the old-school Cartel
godfathers with a campaign of violence, intimidation and mayhem,
heralding a series of events that has had devastating consequences
for the whole of society. In Young Blood, the explosive follow-up
to The Cartel, bestselling true-crime author Graham Johnson reveals
how the brutal assassination of drug baron Colin 'King Cocaine'
Smith in 2007 by a group of young bucks triggered the rise of the
foot soldier, and exposes the bitter struggle that has spread
throughout Europe as various factions battle to seize control of
the most lucrative crime syndicate in British history.
This collection of eight 'lectures' by internationally acclaimed
pianist, Graham Johnson, is based on a series of concert talks
given at the Guildhall School of Music and Drama as part of the
Benjamin Britten festival in 2001. The focus of the book is on
Britten's songs, starting with his earliest compositions in the
genre. Graham Johnson suggests that the nature of Britten's
creativity is especially apparent in his setting of poetry, that he
becomes the poet's alter-ego. A chapter on Britten's settings of
Auden and Eliot explores the particular influences these writers
brought to bear at opposite poles of the composer's life. The
inspiration of fellow musicians is also discussed, with a chapter
devoted to Britten's time in Russia and his friendship with the
Rostropovitch family. Closer to home, the book places in context
Britten's folksong settings, illustrating how he subverted the
English folksong tradition by refusing to accept previous
definitions of what constituted national loyalty. Drawing on
letters and diaries, and featuring a number of previously
unpublished photographs, this book illuminates aspects of Britten's
songs from the personal perspective of the pianist who worked
closely with Peter Pears after Benjamin Britten was unable to
perform through illness. Johnson worked with Pears on learning the
role of Aschenbach in 'Death in Venice' and was official pianist
for the first master class given by Peter Pears at Snape in 1972.
This collection of essays examines the 'Grimmian Revolution', the
paradigm shift in the humanities that came with the publication of
Jacob Grimm's Deutsche Grammatik. In doing so, they honour T.A.
Shippey, who has been a leading figure in reconsidering the
contributions of the Old Philology and its impact on the
humanities, particularly the rediscovery of the ancient languages
and literatures of Northern Europe; the role this has played in the
creation of national and regional identities; the attempts to
extend the methods of comparative philology to comparative
mythology; and the collection of folktales, folk-ballads, and the
development of folkloristics. The sixteen essays in this collection
focus on the impact made by nineteenth- and early-twentieth-century
philology in the fields of medieval studies and language studies,
and in the construction of Northern European national identities,
mythologies, and folklore.
Fun and educational, these unique playing cards are beautifully
illustrated with detailed cells and cellular structures - perfect
for science lovers and cell biologists of all ages! Card faces
features favorite illustrations from the textbook Cell Biology by
Thomas D. Pollard et al. - from the clathrin triskelion and its
three-fold symmetry on the 3 to mitotic chromosome structure on the
Queen! Standard 52-card deck with illustrations of echinospherium,
seipin ring, muscle thin filament with troponin-tropomyosin, and
more. Jokers feature illustrations of cdk2-cyclin A (red joker) and
endoplasmic reticulum (black joker). Fourteen different card faces
in all featuring the well-loved cellular illustrations of Graham
Johnson!
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Against the Trend (Paperback)
Anne-Louise Critchlow; Foreword by Graham Johnson
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R803
R659
Discovery Miles 6 590
Save R144 (18%)
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Ships in 10 - 15 working days
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Against the Trend (Hardcover)
Anne-Louise Critchlow; Foreword by Graham Johnson
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R1,305
R1,028
Discovery Miles 10 280
Save R277 (21%)
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Ships in 10 - 15 working days
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English soprano Felicity Lott performs this premier recording of
Poulenc's one-act opera for one character, based on Jean Cocteau's
1930 play. The story revolves around one woman speaking on the
telephone with her (invisible and inaudible) departing lover, who
is leaving her to marry another woman.
Fun and educational, these unique playing cards are beautifully
illustrated with detailed cells and cellular structures - perfect
for science lovers and cell biologists of all ages! Card faces
features favorite illustrations from the textbook Cell Biology by
Thomas D. Pollard et al. - from the clathrin triskelion and its
three-fold symmetry on the 3 to mitotic chromosome structure on the
Queen! Standard 52-card deck with illustrations of endosomes and
lysosome, mother and daughter centrioles, membrane traffic,
eukaryotic phylogenetic tree, three cytoskeletal polymers, and
more. Jokers feature illustrations of autophagy (red joker) and
ribosome, V-type ATPase, CRISPR/Cas, bacterium (black joker).
Fourteen different card faces in all featuring the well-loved
cellular illustrations of Graham Johnson. Includes 12 individual
decks of cards.
A global workforce. Billions in sales. But, unlike Tesco or BP, few
have heard of it. The Cartel is Britain's biggest drugs
organisation, a shadowy network stretching from the freezing,
fog-banks of the Mersey to the glittering marinas of Marbella, from
the coffee shops of Amsterdam to the trading floors of Canary
Wharf. Run by godfathers as rich as Branson but kept in line by a
new generation of teenage killers. Here is the inside story.
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