A trustworthy record is one that is both an accurate statement of facts and a genuine manifestation of those facts. Record trustworthiness thus has two qualitative dimensions: reliability and authenticity. Reliability means that the record is capable of standing for the facts to which it attests, while authenticity means that the record is what it claims to be. This study explores the evolution of the principles and methods for determining record trustworthiness from antiquity to the digital age, and from the perspectives of law and history. It also examines recent efforts undertaken by researchers in the field of archival science to develop methods for ensuring the trustworthiness of records created and maintained in electronic systems. Audience: The target audience for this study is legal scholars working in the field of evidence law, historians working in the field of historical methodology, and recordkeeping professionals (records managers, information technology specialists, archivists) working on the design and implementation of contemporary organizational recordkeeping systems.

By Terry Eastwood This book reports the findings of a research project on the means of protecting the integrity of active and semi-active electronic records. The project, which is commonly referred to as "the UBC Project," was conceived by two of the authors of this book, Luciana Duranti and Terry Eastwood, and conducted between 1994 and 1997. The third author, Heather MacNeil, who worked formally as the principal research assistant on the project, acted as an equal in the research and in the writing of this book. The project investigated a number of fundamental questions that have arisen over the past decade as a consequence of the rapid development and use of computer technology for the creation, maintenance, and preservation of recorded information. One of the first comprehensive studies of the issues associated with the management of electronic records was conducted by the United Nations. The study, commonly known as the ACCIS report, aimed to "develop guidelines for implementation of electronic archives and records management programmes for use by United Nations organizations, taking into account traditional archives and records management practices. " The report of the study of electronic records in eighteen United Nations organizations identified a number of enduring issues. It recognized that the United Nations had to "distinguish between record and non-record material. "l It recognized the problem of ensuring the authenticity of records, which, rather narrowly, it construed as "assuring legality.

Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life. In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.

An extremely useful text for research Internationally renowned experts describe the models, provide data obtained with those models, and discuss the relative usefulness of models in relation to the diabetic syndrome in humans. The first section examines the most widely used model, the streptozotocin (STZ) rat, condensing a massive quantity of literature to present both the general effects of of STZ diabetes and the effects on individual organ systems. The second section discusses less well-known and more recent diabetic models, such as the BB rat, the NOD mouse and Zucker and Zucker Diabetic Fatty rat models.
Genetic models of insulin dependent diabetes mellitus (IDDM) are examined and compared to chemically induced IDDM models.

World-historical questions such as these, the subjects of major works by Jared Diamond, David Landes, and others, are now of great moment as global frictions increase. In a spirited and original contribution to this quickening discussion, two renowned historians, father and son, explore the webs that have drawn humans together in patterns of interaction and exchange, cooperation and competition, since earliest times. Whether small or large, loose or dense, these webs have provided the medium for the movement of ideas, goods, power, and money within and across cultures, societies, and nations. From the thin, localized webs that characterized agricultural communities twelve thousand years ago, through the denser, more interactive metropolitan webs that surrounded ancient Sumer, Athens, and Timbuktu, to the electrified global web that today envelops virtually the entire world in a maelstrom of cooperation and competition, J. R. McNeill and William H. McNeill show human webs to be a key component of world history and a revealing framework of analysis. Avoiding any determinism, environmental or cultural, the McNeills give us a synthesizing picture of the big patterns of world history in a rich, open-ended, concise account.

Measurement of Cardiac Function presents detailed descriptions of how to set up and use several classical cardiac preparations from scratch. The preparations include whole heart, atrial, ventricular, and papillary muscles and in vivo small animal preparations. Methods for monitoring contraction and contractility are fully described. Flow charts and step-by-step instructions make it easy to understand, even for the first time investigator.
This book examines the most widely used tools in experimental cardiology and provides you with the recipe-setting up the technique, procurement of equipment, sample data and calculations, problems and trouble shooting, adapting to other species, modifications, and applicability. Undoubtedly, this text will be a great asset to cardiovascular physiologists, pharmacologists, experimental cardiologists, and students of physiology and pharmacology.

"The Rise of the West," winner of the National Book Award for history in 1964, is famous for its ambitious scope and intellectual rigor. In it, McNeill challenges the Spengler-Toynbee view that a number of separate civilizations pursued essentially independent careers, and argues instead that human cultures interacted at every stage of their history. The author suggests that from the Neolithic beginnings of grain agriculture to the present major social changes in all parts of the world were triggered by new or newly important foreign stimuli, and he presents a persuasive narrative of world history to support this claim.
In a retrospective essay titled ""The Rise of the West" after Twenty-five Years," McNeill shows how his book was shaped by the time and place in which it was written (1954-63). He discusses how historiography subsequently developed and suggests how his portrait of the world's past in The Rise of the West should be revised to reflect these changes.
"This is not only the most learned and the most intelligent, it is also the most stimulating and fascinating book that has ever set out to recount and explain the whole history of mankind. . . . To read it is a great experience. It leaves echoes to reverberate, and seeds to germinate in the mind."--H. R. Trevor-Roper, "New York Times Book Review "

Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life. In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.

By Terry Eastwood This book reports the findings of a research project on the means of protecting the integrity of active and semi-active electronic records. The project, which is commonly referred to as "the UBC Project," was conceived by two of the authors of this book, Luciana Duranti and Terry Eastwood, and conducted between 1994 and 1997. The third author, Heather MacNeil, who worked formally as the principal research assistant on the project, acted as an equal in the research and in the writing of this book. The project investigated a number of fundamental questions that have arisen over the past decade as a consequence of the rapid development and use of computer technology for the creation, maintenance, and preservation of recorded information. One of the first comprehensive studies of the issues associated with the management of electronic records was conducted by the United Nations. The study, commonly known as the ACCIS report, aimed to "develop guidelines for implementation of electronic archives and records management programmes for use by United Nations organizations, taking into account traditional archives and records management practices. " The report of the study of electronic records in eighteen United Nations organizations identified a number of enduring issues. It recognized that the United Nations had to "distinguish between record and non-record material. "l It recognized the problem of ensuring the authenticity of records, which, rather narrowly, it construed as "assuring legality.

A trustworthy record is one that is both an accurate statement of facts and a genuine manifestation of those facts. Record trustworthiness thus has two qualitative dimensions: reliability and authenticity. Reliability means that the record is capable of standing for the facts to which it attests, while authenticity means that the record is what it claims to be. This study explores the evolution of the principles and methods for determining record trustworthiness from antiquity to the digital age, and from the perspectives of law and history. It also examines recent efforts undertaken by researchers in the field of archival science to develop methods for ensuring the trustworthiness of records created and maintained in electronic systems. Audience: The target audience for this study is legal scholars working in the field of evidence law, historians working in the field of historical methodology, and recordkeeping professionals (records managers, information technology specialists, archivists) working on the design and implementation of contemporary organizational recordkeeping systems.

Master the 40 basic elements essential to all riders in the classic disciplines of dressage, jumping, and eventing with this book and 90-minute DVD showing action sequences for each fundamental. These fundamentals include correct seat, leg, and hand positions for the rider; the three basic gaits of walk, trot, and canter; how to perform halt and half-halt; how to direct a horse's movement correctly and energetically; the stages of the training scale (rhythm, looseness, contact, impulsion, straightness, and collection); and how to perform basic schooling figures in the arena, from circles and serpentines to diagonals. Each fundamental is defined and explained in text and photos throughout the book, as well as in the 90-minute DVD, with an emphasis on how to avoid common errors. The DVD won a Telly Award for excellence in video production.

Renowned historian William H. McNeil provides a brilliant narrative chronology of the development of Western civilization, representing its socio-political as well as cultural aspects. This sixth edition includes new material for the twentieth-century period and completely revised bibliographies. An invaluable tool for the study of Western civilization, the "Handbook" is an essential complement to readings in primary and secondary sources such as those in the nine-volume "University of Chicago Readings in Western Civilization."

An introduction to a new way of looking at history, from a perspective that stretches from the beginning of time to the present day, "Maps of Time "is world history on an unprecedented scale. Beginning with the Big Bang, David Christian views the interaction of the natural world with the more recent arrivals in flora and fauna, including human beings.
Cosmology, geology, archeology, and population and environmental studies--all figure in David Christian's account, which is an ambitious overview of the emerging field of "Big History." "Maps of Time "opens with the origins of the universe, the stars and the galaxies, the sun and the solar system, including the earth, and conducts readers through the evolution of the planet before human habitation. It surveys the development of human society from the Paleolithic era through the transition to agriculture, the emergence of cities and states, and the birth of the modern, industrial period right up to intimations of possible futures. Sweeping in scope, finely focused in its minute detail, this riveting account of the known world, from the inception of space-time to the prospects of global warming, lays the groundwork for world history--and Big History--true as never before to its name.

In this magnificent synthesis of military, technological, and social history, William H. McNeill explores a whole millennium of human upheaval and traces the path by which we have arrived at the frightening dilemmas that now confront us. McNeill moves with equal mastery from the crossbow--banned by the Church in 1139 as too lethal for Christians to use against one another--to the nuclear missile, from the sociological consequences of drill in the seventeenth century to the emergence of the military-industrial complex in the twentieth. His central argument is that a commercial transformation of world society in the eleventh century caused military activity to respond increasingly to market forces as well as to the commands of rulers. Only in our own time, suggests McNeill, are command economies replacing the market control of large-scale human effort. The Pursuit of Power does not solve the problems of the present, but its discoveries, hypotheses, and sheer breadth of learning do offer a perspective on our current fears and, as McNeill hopes, "a ground for wiser action."
"No summary can do justice to McNeill's intricate, encyclopedic treatment. . . . McNeill's erudition is stunning, as he moves easily from European to Chinese and Islamic cultures and from military and technological to socio-economic and political developments. The result is a grand synthesis of sweeping proportions and interdisciplinary character that tells us almost as much about the history of butter as the history of guns. . . . McNeill's larger accomplishment is to remind us that all humankind has a shared past and, particularly with regard to its choice of weapons and warfare, a shared stake in thefuture."--Stuart Rochester, "Washington Post Book World"
"Mr. McNeill's comprehensiveness and sensitivity do for the reader what Henry James said that Turgenev's conversation did for him: they suggest 'all sorts of valuable things.' This narrative of rationality applied to irrational purposes and of ingenuity cannibalizing itself is a work of clarity, which delineates mysteries. The greatest of them, to my mind, is why human beings have never learned to cherish their own species."--Naomi Bliven, "The New Yorker
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In this magisterial history, National Book Award winner William H. McNeill chronicles the interactions and disputes between Latin Christians and the Orthodox communities of eastern Europe during the period 1081-1797. Concentrating on Venice as the hinge of European history in the late medieval and early modern period, McNeill explores the technological, economic, and political bases of Venetian power and wealth, and the city's unique status at the frontier between the papal and Orthodox Christian worlds. He pays particular attention to Venetian influence upon southeastern Europe, and from such an angle of vision, the familiar pattern of European history changes shape.
"No other historian would have been capable of writing a book as direct, as well-informed and as little weighed down by purple prose as this one. Or as impartial. McNeill has succeeded admirably."--Fernand Braudel, "Times Literary Supplement"
"The book is serious, interesting, occasionally compelling, and always suggestive."--Stanley Chojnacki, "American Historical Review"

Upon its original publication, Plagues and Peoples was an immediate critical and popular success, offering a radically new interpretation of world history as seen through the extraordinary impact--political, demographic, ecological, and psychological--of disease on cultures. From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, the history of disease is the history of humankind. With the identification of AIDS in the early 1980s, another chapter has been added to this chronicle of events, which William McNeill explores in his new introduction to this updated editon.

Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening. "A brilliantly conceptualized and challenging achievement" (Kirkus Reviews), it is essential reading, offering a new perspective on human history.

World Environmental History, a Berkshire Essential, explores how the biosphere is affected by human interventions such as climate change, deforestation, waste management, water and wind energy, population growth, oil spills, ecological imperialism, and urbanization. An interdisciplinary approach to the field considers biological and physical processes as integral parts of history, with mammals, birds, plants, bacteria, and viruses as "biotic actors" that play important roles. So do geological formations and disruptions, such as deserts, mountains, islands, earthquakes, and tsunamis. The volume's rich content includes articles on the anthroposphere, carrying capacity, ethnobotany, Gaia theory, and the Green Revolution, for instance-all of which define key concepts that shape the environmental studies so crucial to a sustainable future.

"The Islamic World" is a collection of important and representative documents from all periods of Islamic history. From the formative years in Arabia to the confrontations with and responses to modernity, these translations indicate the continuity and development of the youngest of the world's greatest civilizations. Included are historical, theological, philosophical, and political writings, as well as poetry and narratives, from Muslim writers in the Arab lands, Turkey, Persia, and other parts of the Islamic world. The editors have provided informative introductions to each historical period and to the individual texts, making this an enlightening and intriguing first look at Islamic civilization and tradition.

Africa in World History stresses Africa's interrelatedness to other regions and cultures, from early trade routes, the arrival of Christianity and Islam, and the ramifications of colonialism to contemporary issues such as HIV/AIDS and apartheid that have thwarted Africa's efforts to establish unity. Africa stretches across more than 11 million square miles, from the Sahara and Sahel in the north to the mineral-resource-rich south, the endangered rain forests of the west, and the Serengeti savannas of the east. Fossils from Ethiopia tell us that the human species originated in Africa, and scholars have different theories about the journey out of Africa made by Homo sapiens some 60,000 years ago. Today, Africa is home to over 1 billion people speaking more than a thousand different languages.

Arnold Toynbee was one of the most remarkable thinkers of the 20th century, a man of far-reaching imagination, extraordinary erudition, and an infinite capacity for hard work. At the height of his fame, he was the most renowned scholar in the world, acclaimed as the author of the monumental, 10-volume A Study of History. Indeed, such was the regard for his Study that Time magazine, in a cover article on Toynbee published in 1947, declared that he had "found history Ptolemaic and left it Copernican."
In Arnold Toynbee: A Life, William H. McNeill weaves together Toynbee's intellectual accomplishments and the personal difficulties of his private life, providing both an intimate portrait of a leading thinker and a judicious evaluation of Toynbee's work and his legacy for the study of history. McNeill illuminates the strengths and weaknesses of A Study of History as well as the countless other works penned by this prolific writer, examining the responses of other historians (including the devastating attack mounted by Hugh Trevor Roper) and Toynbee's attempts to modify his Study to answer these criticisms. And McNeill also examines Toynbee's tormented personal life, including his troubled marriage to Rosalind Murray (the daughter of Gilbert Murray), and the suicide of his son Anthony. What emerges is both poignant and thought-provoking, a biography and a commentary about how history is written and how it should be pursued.
William McNeill is one of America's most eminent historians, the winner of a National Book Award in 1964 for The Rise of the West, which The New York Times Book Review called "the most learned...the most intelligent...the most stimulating and fascinating bookthat has ever set out to recount and explain the whole history of the world." In this sympathetic portrait of a life both triumphant and troubled, McNeill brings his skills to bear on one of the greatest figures in his field, illuminating a career of rare accomplishment.

In this magnificent synthesis of military, technological, and social history, William H. McNeill explores a whole millennium of human upheaval and traces the path by which we have arrived at the frightening dilemmas that now confront us. McNeill moves with equal mastery from the crossbow--banned by the Church in 1139 as too lethal for Christians to use against one another--to the nuclear missile, from the sociological consequences of drill in the seventeenth century to the emergence of the military-industrial complex in the twentieth. His central argument is that a commercial transformation of world society in the eleventh century caused military activity to respond increasingly to market forces as well as to the commands of rulers. Only in our own time, suggests McNeill, are command economies replacing the market control of large-scale human effort. The Pursuit of Power does not solve the problems of the present, but its discoveries, hypotheses, and sheer breadth of learning do offer a perspective on our current fears and, as McNeill hopes, "a ground for wiser action."
"No summary can do justice to McNeill's intricate, encyclopedic treatment. . . . McNeill's erudition is stunning, as he moves easily from European to Chinese and Islamic cultures and from military and technological to socio-economic and political developments. The result is a grand synthesis of sweeping proportions and interdisciplinary character that tells us almost as much about the history of butter as the history of guns. . . . McNeill's larger accomplishment is to remind us that all humankind has a shared past and, particularly with regard to its choice of weapons and warfare, a shared stake in thefuture."--Stuart Rochester, "Washington Post Book World"
"Mr. McNeill's comprehensiveness and sensitivity do for the reader what Henry James said that Turgenev's conversation did for him: they suggest 'all sorts of valuable things.' This narrative of rationality applied to irrational purposes and of ingenuity cannibalizing itself is a work of clarity, which delineates mysteries. The greatest of them, to my mind, is why human beings have never learned to cherish their own species."--Naomi Bliven, "The New Yorker
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