This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various invertebrates and vertebrates, and the causes of congenital malformations. In the main part, the developmental disorders of the human brain and the spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These are underlined by carefully chosen clinical case studies, including imaging data and, when available, postmortem verification of the developmental disorders involved. Numerous color photographs and illustrations complement the text. This second edition emphasizes the prenatal diagnosis by ultrasound, MRI, and DTI and implements new classifications of developmental disorders.

This book is unique in that it provides the reader with the most up-to-date terminology used to describe the human nervous system (central and peripheral) and the related sensory organs, i.e., the Terminologia Neuroanatomica (TNA), the official terminology of the IFAA (International Federation of Associations of Anatomists). The book provides a succinct but detailed review of the neuroanatomical structures of the human body and will greatly benefit not only various specialists such as (neuro)anatomists, neurologists and neuroscientists, but also students taking neuroanatomy and neuroscience courses. The book offers a high yield, combined presentation of neuroanatomical illustrations and text and provides the reader a 'one-stop source' for studying the intricacies of the human nervous system and its sensory organs. It includes an alphabetical list of official English terms and synonyms with the official Latin terms and synonyms from the TNA. With regard to the entries, the name of the item in standardized English is provided, followed by synonyms and the official TNA Latin term, Latin synonyms and eponyms, a short description and in many cases one or more illustrations. To facilitate the use of illustrations, certain entries such as the gyri or sulci of the cerebral cortex are presented together with extensive cross-references. Terms that form part of a certain structure (such as the amygdaloid body, the thalamus and the hypothalamus) are listed under the respective structure. Segments and branches of arteries are discussed under the main artery, for example the A1-A5 segments under the anterior cerebral artery. Most nerves can be found following their origin from the brachial, cervical and lumbosacral plexuses. However, the major nerves of the limbs are discussed separately, as are the cranial nerves. Nuclei can be found by their English name or under Nuclei by their eponym.

Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death may progress through connections. Knowledge of how the various parts of the brain are interconnected to form functional systems is a prerequisite for the proper understanding of data from all fields in the neurosciences.

"Clinical Neuroanatomy: Brain Circuitry and Its Disorders" bridges the gap between neuroanatomy and clinical neurology. It emphasizes human and primate data in the context of disorders of brain circuitry which are so common in neurological practice. In addition, numerous clinical cases demonstrate how normal brain circuitry may be interrupted and to what effect. Following an introduction into the organization and vascularisation of the human brain and the techniques to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, autonomic and limbic systems, the cerebral cortex and complex cerebral functions.

Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death can progress through connections. Accordingly, knowing how the various parts of the brain are interconnected to form functional systems is a prerequisite for properly understanding data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It focuses on human and primate data in the context of brain circuitry disorders, which are so common in neurological practice. In addition, numerous clinical cases are presented to demonstrate how normal brain circuitry can be interrupted, and what the effects are. Following an introduction to the organization and vascularization of the human brain and the techniques used to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, autonomic and limbic systems, the cerebral cortex and complex cerebral functions. In this 2nd edition, apart from a general updating, many new illustrations have been added and more emphasis is placed on modern techniques such as diffusion magnetic resonance imaging (dMRI) and network analysis. Moreover, a developmental ontology based on the prosomeric model is applied, resulting in a more modern subdivision of the brain. The new edition of Clinical Neuroanatomy is primarily intended for neurologists, neuroradiologists and neuropathologists, as well as residents in these fields, but will also appeal to (neuro)anatomists and all those whose work involves human brain mapping.

This book is unique in that it provides the reader with the most up-to-date terminology used to describe the human nervous system (central and peripheral) and the related sensory organs, i.e., the Terminologia Neuroanatomica (TNA), the official terminology of the IFAA (International Federation of Associations of Anatomists). The book provides a succinct but detailed review of the neuroanatomical structures of the human body and will greatly benefit not only various specialists such as (neuro)anatomists, neurologists and neuroscientists, but also students taking neuroanatomy and neuroscience courses. The book offers a high yield, combined presentation of neuroanatomical illustrations and text and provides the reader a 'one-stop source' for studying the intricacies of the human nervous system and its sensory organs. It includes an alphabetical list of official English terms and synonyms with the official Latin terms and synonyms from the TNA. With regard to the entries, the name of the item in standardized English is provided, followed by synonyms and the official TNA Latin term, Latin synonyms and eponyms, a short description and in many cases one or more illustrations. To facilitate the use of illustrations, certain entries such as the gyri or sulci of the cerebral cortex are presented together with extensive cross-references. Terms that form part of a certain structure (such as the amygdaloid body, the thalamus and the hypothalamus) are listed under the respective structure. Segments and branches of arteries are discussed under the main artery, for example the A1-A5 segments under the anterior cerebral artery. Most nerves can be found following their origin from the brachial, cervical and lumbosacral plexuses. However, the major nerves of the limbs are discussed separately, as are the cranial nerves. Nuclei can be found by their English name or under Nuclei by their eponym.

Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death may progress through connections. Knowledge of how the various parts of the brain are interconnected to form functional systems is a prerequisite for the proper understanding of data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It emphasizes human and primate data in the context of disorders of brain circuitry which are so common in neurological practice. In addition, numerous clinical cases demonstrate how normal brain circuitry may be interrupted and to what effect. Following an introduction into the organization and vascularisation of the human brain and the techniques to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, autonomic and limbic systems, the cerebral cortex and complex cerebral functions.

This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various invertebrates and vertebrates, and the causes of congenital malformations. In the main part, the developmental disorders of the human brain and the spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These are underlined by carefully chosen clinical case studies, including imaging data and, when available, postmortem verification of the developmental disorders involved. Numerous color photographs and illustrations complement the text. This second edition emphasizes the prenatal diagnosis by ultrasound, MRI, and DTI and implements new classifications of developmental disorders.

This comprehensive reference is clearly destined to become the definitive anatomical basis for all molecular neuroscience research. The three volumes provide a complete overview and comparison of the structural organisation of all vertebrate groups, ranging from amphioxus and lamprey through fishes, amphibians and birds to mammals. This thus allows a systematic treatment of the concepts and methodology found in modern comparative neuroscience. Neuroscientists, comparative morphologists and anatomists will all benefit from: * 1,200 detailed and standardised neuroanatomical drawings * the illustrations were painstakingly hand-drawn by a team of graphic designers, specially commissioned by the authors, over a period of 25 years * functional correlations of vertebrate brains * concepts and methodology of modern comparative neuroscience * five full-colour posters giving an overview of the central nervous system of the vertebrates, ideal for mounting and display This monumental work is, and will remain, unique; the only source of such brilliant illustrations at both the macroscopic and microscopic levels.