Enriched Numerical Techniques: Implementation and Applications explores recent advances in enriched numerical techniques, including the extended finite element method, meshfree methods, extended isogeometric analysis and coupled numerical techniques. Techniques for implementation and programming issues are discussed, with other sections discussing applications for enriched numerical techniques in solving a range of engineering problems. The level set methodologies for complex shaped irregularities is presented, as are enriched numerical methodologies for various complex and advanced problems such as Nonlinear Structural Analysis, Fracture and Fatigue in Structures, Elasto-Plastic Crack Growth, Large Deformation Analysis, Frictional Contact Problems, Thermo-Mechanical Problems, Fluid Flow Investigations, Composite Materials and Bio-mechanics.

This new 2-volume set explores new research and perspectives in genetic engineering, which enables the precise control of the genetic composition and gene expression of organism. This powerful technology can be used for environmental sustainability, food and nutritional security, medicinal advancement, and more. Genetic Engineering aims to provide a deep understanding of the many aspects of this emerging technology and its diverse applications. Genetic Engineering, Volume 1: Principles, Mechanism, and Expression covers genetic engineering concepts, molecular tools, and technologies utilized in the manipulation, amplification, and introgression of DNA. The volume explains the concepts of genetic engineering, enzymes of genetic engineering, and tools used in genetic engineering. It provides an introduction of recombinant DNA into host cells and discusses the linking of desired gene with DNA vector/gene cloning vector, polymerase chain reactions, the concept and nature of genes, blotting techniques, chromosome jumping, electrophoresis, genetically engineered microorganisms, and molecular markers and their applications. Genetic Engineering, Volume 2: Applications, Bioethics, and Biosafety expresses the various appreciation and challenges of genetic engineering and issues related to bioethics and biosafety. Chapters cover the legal issues of genetic engineering, including intellectual property rights (IPR) and protection (IPP) and the patenting of living organisms, copyrights, trade secrets, and trademarks. The volume considers the safety and benefits of genetic engineering in human welfare, such as in genetically engineered Bt and Bt cotton, along with the biohazards of recombinant DNA technology. Chapters explain genetically modified organisms and microorganisms, genetic engineering of horticultural crops, genetic engineering in the agricultural sciences, and more. This 2-volume book will be a valuable asset to upper-level students in cell biology as well as to faculty and researchers involved in genetics, molecular genetics, biochemistry, biotechnology, botany, zoology and agriculture sciences.

This two-volume book is a valuable resource to students, researchers, scientists, commercial producers, consultants and policymakers interested in agriculture or plant sciences particularly in date palm biotechnology. Date Palm Biotechnology Protocols, Volume 1: Tissue Culture and Applications is comprised of 27 chapters covering adventitious organogenesis, somatic embryogenesis, contamination, hyperhydricity, acclimatization, cell suspension, protoplast and bioreactors, genetic transformation secondary metabolites, and abiotic stress. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Date Palm Biotechnology Protocols, Volume 1: Tissue Culture and Applications aims to supplement the previous volume and to provide precise stepwise protocols in the field of date palm biotechnology.

Created during and after the Second World War, the British Welfare State seemed to promise welfare for all, but, in its original form, excluded millions of disabled people. This book examines attempts in the subsequent three decades to reverse this exclusion. It is the first to contextualise disability historically in the welfare state and under each government of the period. It looks at how disability policy and perceptions were slow to change as a welfare issue, which is very timely in today's climate of austerity. It also provides the first major analysis of the Disablement Income Group, one of the most powerful pressure groups in the period and the 1972 Thalidomide campaign and its effect on the Heath government. Given the recent emergence of the history of disability in Britain as a major area of research, the book will be ideal for academics, students and activists seeking a better understanding of the topic.

This important reference book is the first comprehensive resource worldwide that reflects research achievements in date palm biotechnology, documenting research events during the last four decades, current status, and future outlook. This book is essential for researchers, policy makers, and commercial entrepreneurs concerned with date palm. The book is invaluable for date palm biotechnology students and specialists. This monument is written by an international team of experienced researchers from both academia and industry. It consists of five sections covering all aspects of date palm biotechnology including A) Micropropagation, B) Somaclonal Variation, Mutation and Selection, C) Germplasm Biodiversity and Conservation, D) Genetics and Genetic Improvement, and E) Metabolites and Industrial Biotechnology. The book brings together the principles and practices of contemporary date palm biotechnology. Each chapter contains background knowledge related to the topic, followed by a comprehensive literature review of research methodology and results including the authors own experience including illustrative tables and photographs."

The 2030 agenda for development, or what is known as the Sustainable Development Goals (SDGs), is perhaps the most ambitious agenda collectively agreed upon by 193 countries in human history. Yet, the framers of the 2030 agenda for development forgot to dedicate one goal focused on the role of communication in achieving the SDGs. Such oversight has attracted the attention of media and communication scholars alike, journalists, and policymakers who understand that it is nearly impossible to achieve the SDGs without the articulation and embrace of the role of communication in development. Volume 2 provides in-depth and specific explorations into regional perspectives concerning communication and the SDGs, with research on a rich array of sources, including Latin America, Africa, Australia, as well as special cases relating to timely studies such as social media, COVID-19, marginalized voices, and women's equality.  

This important 2-volume reference book is the first comprehensive resource reflecting the current global status and prospects of date palm cultivation by country. This volume covers Asia and Europe. The Asian countries included are: Iran, Saudi Arabia, Iraq, Pakistan, Oman, Yemen, Israel, Kuwait, Qatar, Bahrain, Syria, Palestine and India. Europe is represented by Spain. Topics discussed are: cultivation practices; genetic resources and breeding; conservation and germplasm banks; cultivar classification and identification based on morphological and molecular markers; micropropagation and progress toward scale-up production; and advances in dates processing and marketing. Chapters are supported by tables and color photographs. Appendixes summarize traits and distribution of major cultivars, commercial resources of offshoots and in vitro plants; and institutions and scientific societies concerned with date palm.

Provides a contemporary view of the impact of climate change on cultivation of various fruit species. Offers modern approaches for mitigating the adverse impact of climate change on fruits cultivation. Describes case studies, empirical experiments and observations emphasizing the research progress of understanding and combating the impact of climate change on fruits production. Illustrates presented concepts with relevant figures and tabulated data.

The 2030 agenda for development, or what is known as the Sustainable Development Goals (SDGs), is the most ambitious agenda collectively agreed upon by 193 countries in human history. In 2015, the UN Member States adopted the 17 SDGs as a framework that would help address the challenges being faced by humanity. From eradicating poverty, ending hunger, providing universal access to healthcare and education, and addressing climate change; to the partnering of individuals, communities, and nation-states to achieve global goals. Yet, the framers of the 2030 agenda forgot to dedicate one goal focused on the role of communication in achieving the SDGs. It is nearly impossible to achieve the SDGs without the articulation and embrace of the role of communication in development. Today, development has become a communication issue, and communication is a development issue. How could such a vital pillar of life be missing in the UN's Sustainable Development Goals? Volume 1 provides an overview of what the contributors have termed as the 'missing link' between existing SDGs: Communication for All.

The Palgrave Handbook of International Communication and Sustainable Development is a major resource for stakeholders interested in understanding the role of communication in achieving the UN'S Sustainable Development Goals. Bringing together theoretical and applied contributions from scholars in Europe, Africa, the Middle East, Asia and North America, the handbook argues that communication is a key factor in achieving the global goals and suggests a review of the SDGs to consider its importance. Reflecting on the impact of COVID-19, it highlights the need for effective communication infrastructure and critically assesses the 2030 agenda and timeline. Including individual SDG and country case studies as well as integrated analysis, the chapters seek to enrich understanding of communication for development and propose crucial policy interventions. It is critical reading for researchers as well as policy makers and NGOs.

This book is the first volume of a comprehensive assemblage of contemporary knowledge relevant to genomics and other omics in date palm. Volume 1 consists of 11 chapters arranged in 3 parts grouped according to subject. Part I, Biology and Phylogeny, focuses on date palm biology, evolution and origin. Part II, Biodiversity and Molecular Identification, covers conformity of in vitro derived plants, molecular markers, barcoding, pollinizer genetics and gender determination. Part III, Genome Mapping and Bioinformatics, addresses genome mapping of nuclear, chloroplast and mitochondrial DNA, in addition to a chapter on progress made in date palm bioinformatics. This volume represents the efforts of 30 international scientists from 10 countries and contains 78 figures and 30 tables to illustrate presented concepts. Volume 2 is published under the title: Omics and Molecular Breeding.

This important 2-volume reference book is the first comprehensive resource reflecting the current global status and prospects of date palm cultivation by country. This volume covers Africa and the Americas. Countries included are: Egypt, Algeria, Sudan, Tunisia, Libya, Morocco, Mauritania, Niger, Cameroon, Djibouti, Chad, Mali Somalia, Ethiopia, Burkina Faso and Senegal, as well as the United States of America and the South American countries Chile and Peru. Topics discussed are: cultivation practices; genetic resources and breeding; conservation and germplasm banks; cultivar classification and identification based on morphological and molecular markers; micropropagation and progress toward scale-up production; and advances in dates processing and marketing. Chapters are supported by tables and color photographs. Appendixes summarize traits and distribution of major cultivars, commercial resources of offshoots and in vitro plants; and institutions and scientific societies concerned with date palm.

Provides a contemporary view of the impact of climate change on cultivation of various fruit species. Offers modern approaches for mitigating the adverse impact of climate change on fruits cultivation. Describes case studies, empirical experiments and observations emphasizing the research progress of understanding and combating the impact of climate change on fruits production. Illustrates concepts with relevant figures and tabulated data.

This clear and concise text covers all the assessable aspects of the ENT curriculum for the FRCS. Although technique and presentation of knowledge will no doubt be attained through viva practice, the comprehensive content ensures that all candidates have the relevant knowledge not only to succeed, but also to excel in their viva examination. Covering both the theoretical and clinical aspects of the examination, as well as other equally critical aspects, including communication skills, clinical examination and miscellaneous sections, this handbook is a high yield revision aid for all surgical trainees in the early stages of their Otolaryngology careers, and simultaneously acts as an emergency information source for those cross-covering the specialty. ENT and Otorhinolaryngology surgical trainees and Residents will find the scope of this guide highly relevant to obtain FRCS accreditation or equivalent.

Ethics and the Good Doctor brings together existing literature and an analysis of empirical research conducted by the Jubilee Centre for Character and Virtues to examine the ethical nature of medical practice and explore medicine as a virtuous profession. The book is based on the idea that medical practice is an inherently moral profession, in which notions of trust, care and meaningful relationships form the foundations of being a good doctor. By taking into account the ethical dimensions of medical practice that have come under greater scrutiny and pressure over recent years, this book explores how personal and professional character is understood, enacted, and experienced by medical practitioners at various stages of their career. Ethics and the Good Doctor situates and presents the empirical data in a way that is accessible to practicing doctors, medical students, and medical educators. Clear implications for policy, practice, and research are offered, ensuring this book will be of great interest to a range of stakeholders involved in medical practice, including those working in medical policy.

This new 2-volume set explores new research and perspectives in genetic engineering, which enables the precise control of the genetic composition and gene expression of organism. This powerful technology can be used for environmental sustainability, food and nutritional security, medicinal advancement, and more. Genetic Engineering aims to provide a deep understanding of the many aspects of this emerging technology and its diverse applications. Genetic Engineering, Volume 1: Principles, Mechanism, and Expression covers genetic engineering concepts, molecular tools, and technologies utilized in the manipulation, amplification, and introgression of DNA. The volume explains the concepts of genetic engineering, enzymes of genetic engineering, and tools used in genetic engineering. It provides an introduction of recombinant DNA into host cells and discusses the linking of desired gene with DNA vector/gene cloning vector, polymerase chain reactions, the concept and nature of genes, blotting techniques, chromosome jumping, electrophoresis, genetically engineered microorganisms, and molecular markers and their applications. Genetic Engineering, Volume 2: Applications, Bioethics, and Biosafety expresses the various appreciation and challenges of genetic engineering and issues related to bioethics and biosafety. Chapters cover the legal issues of genetic engineering, including intellectual property rights (IPR) and protection (IPP) and the patenting of living organisms, copyrights, trade secrets, and trademarks. The volume considers the safety and benefits of genetic engineering in human welfare, such as in genetically engineered Bt and Bt cotton, along with the biohazards of recombinant DNA technology. Chapters explain genetically modified organisms and microorganisms, genetic engineering of horticultural crops, genetic engineering in the agricultural sciences, and more. This 2-volume book will be a valuable asset to upper-level students in cell biology as well as to faculty and researchers involved in genetics, molecular genetics, biochemistry, biotechnology, botany, zoology and agriculture sciences.

This new 2-volume set explores new research and perspectives in genetic engineering, which enables the precise control of the genetic composition and gene expression of organism. This powerful technology can be used for environmental sustainability, food and nutritional security, medicinal advancement, and more. Genetic Engineering aims to provide a deep understanding of the many aspects of this emerging technology and its diverse applications. Genetic Engineering, Volume 1: Principles, Mechanism, and Expression covers genetic engineering concepts, molecular tools, and technologies utilized in the manipulation, amplification, and introgression of DNA. The volume explains the concepts of genetic engineering, enzymes of genetic engineering, and tools used in genetic engineering. It provides an introduction of recombinant DNA into host cells and discusses the linking of desired gene with DNA vector/gene cloning vector, polymerase chain reactions, the concept and nature of genes, blotting techniques, chromosome jumping, electrophoresis, genetically engineered microorganisms, and molecular markers and their applications. Genetic Engineering, Volume 2: Applications, Bioethics, and Biosafety expresses the various appreciation and challenges of genetic engineering and issues related to bioethics and biosafety. Chapters cover the legal issues of genetic engineering, including intellectual property rights (IPR) and protection (IPP) and the patenting of living organisms, copyrights, trade secrets, and trademarks. The volume considers the safety and benefits of genetic engineering in human welfare, such as in genetically engineered Bt and Bt cotton, along with the biohazards of recombinant DNA technology. Chapters explain genetically modified organisms and microorganisms, genetic engineering of horticultural crops, genetic engineering in the agricultural sciences, and more. This 2-volume book will be a valuable asset to upper-level students in cell biology as well as to faculty and researchers involved in genetics, molecular genetics, biochemistry, biotechnology, botany, zoology and agriculture sciences.

This volume analyses corporate insolvency law as a coherent whole, stemming from common fundamental principles and amenable to being justified or criticised on that basis. The author explains why consistency of principle must be sought and how it might be found in the relevant statutory and case law. He then constructs an egalitarian theory for the analysis of corporate insolvency law, based on the premise that all the parties affected by this law are to be treated as equals. He argues that this theory can reconcile the dictates of fairness with the demands of economic efficiency. The theory is employed to analyse some of the most important aspects of insolvency law. Why should the individualistic method of enforcing claims against solvent companies give way to a collective method during insolvency? Why are there different formal mechanisms for dealing with troubled companies? What role does the pari passu principle play in the distribution of an insolvent company s assets? The controversial issues of whether and when secured creditors should be accorded priority over others receive detailed consideration. The functional role of the floating charge and its relationship with receivership are also analysed in this context. The many questions relating to the operation of the new administration procedure introduced by the Enterprise Act 2002 are considered in the light of principle. The book also analyses the role of the wrongful trading provisions. It examines, finally, why insolvency law objects to certain transactions at an undervalue and those having a preferential effect. This volume aims to enhance understanding of this important branch of the law, and to suggest principled solutions to problems which have not yet received judicial attention.

This handbook considers topics that have general application to the critically ill patient. Basic pathophysiology and understanding of its role in critical care monitoring and management are covered, followed by a close look at trauma related and non-trauma related entities likely to afflict the critically ill surgical patient.The authors consist of practitioners who are experts in their field. They represent the team approach to critical care management where members from the divisions of anesthesia, internal medicine, respiratory medicine, infectious disease and surgical specialties all contribute in formulating intervention, assessment and management plans for the critically ill surgical patient.By emphasising the surgical conditions requiring critical care, The Surgical Critical Care Handbook will serve as a quick and easy reference for any medical trainee or practitioner aspiring to join the ICU.

Regional Parallelism and Corruption Scandals in Nigeria is a ground-breaking book that offers fresh perspectives on the character and role of the African media in covering corruption scandals. It explores whether reports regarding corruption stem from the efforts of journalists who employ investigative journalism, or if it is a mere coincidence promoted by the activities of anti-corruption agencies. To that end, the book develops a media systems theory for Africa based on the coverage of corruption scandals in the Nigerian press. This new theoretical paradigm, defined as regional parallelism, argues that African countries are nations within nations, and that therefore any comparative study of the media system should recognize this understanding. The book combines both interviews with journalists as well as qualitative content analysis of newspapers to determine the patterns and issues that influence the reporting of corruption. It also looks at corruption within the media itself, taking into account factors such as regionalism and ethnicity within the practice of journalism.

The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions. Regulatory agencies have raised the bar for the development and manufacture of antibody-based products, expecting to see the use of Quality by Design (QbD) elements demonstrating an in-depth understanding of product and process based on sound science. Drug delivery systems have become an increasingly important part of the therapy and most biopharmaceuticals for self-administration are being marketed as combination products. A survey of the market indicates that there is a strong need for a new book that will provide "one stop shopping" for the latest information and knowledge of the scientific and engineering advances made over the last few years in the area of biopharmaceutical product development. The new book entitled Development of Biopharmaceutical Drug Device Products is a reference text for scientists and engineers in the biopharmaceutical industry, academia or regulatory agencies. With insightful chapters from experts in the field, this new book reviews first principles, covers recent technological advancements and provides case studies and regulatory strategies relating to the development and manufacture of antibody-based products. It covers topics such as the importance of early preformulation studies during drug discovery to influence molecular selection for development, formulation strategies for new modalities, and the analytical techniques used to characterize them. It also addresses important considerations for later stage development such as the development of robust formulations and processes, including process engineering and modeling of manufacturing unit operations, the design of analytical comparability studies, and characterization of primary containers (pre-filled syringes and vials).Finally, the latter half of the book reviews key considerations to ensure the development and approval of a patient-centered delivery system design. This involves the evolving regulatory framework with perspectives from both the US and EU industry experts, the role of international standards, design control/risk management, human factors and its importance in the product development and regulatory approval process, as well as review of the risk-based approach to bridging between devices used in clinical trials and the to-be-marketed device. Finally, case studies are provided throughout.The typical readership would have biology and/or engineering degrees and would include researchers, scientific leaders, industry specialists and technology developers working in the biopharmaceutical field.

This clear and concise text covers all the assessable aspects of the ENT curriculum for the FRCS. Although technique and presentation of knowledge will no doubt be attained through viva practice, the comprehensive content ensures that all candidates have the relevant knowledge not only to succeed, but also to excel in their viva examination. Covering both the theoretical and clinical aspects of the examination, as well as other equally critical aspects, including communication skills, clinical examination and miscellaneous sections, this handbook is a high yield revision aid for all surgical trainees in the early stages of their Otolaryngology careers, and simultaneously acts as an emergency information source for those cross-covering the specialty. ENT and Otorhinolaryngology surgical trainees and Residents will find the scope of this guide highly relevant to obtain FRCS accreditation or equivalent.