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Research and development in the pharmaceutical industry is a
time-consuming and expensive process, making it difficult for newly
developed drugs to be formulated into commercially available
products. Both formulation and process development can be optimized
by means of statistically organized experiments, artificial
intelligence and other computational methods. Simultaneous
development and investigation of pharmaceutical products and
processes enables application of quality by design concept that is
being promoted by the regulatory authorities worldwide.
Computer-aided applications in pharmaceutical technology covers the
fundamentals of experimental design application and interpretation
in pharmaceutical technology, chemometric methods with emphasis of
their application in process control, neural computing (artificial
neural networks, fuzzy logic and decision trees, evolutionary
computing and genetic algorithms, self-organizing maps),
computer-aided biopharmaceutical characterization as well as
application of computational fluid dynamics in pharmaceutical
technology. All of these techniques are essential tools for
successful building of quality into pharmaceutical products and
processes from the early stage of their development to selection of
the optimal ones. In addition to theoretical aspects of various
methods, the book provides numerous examples of their application
in the field of pharmaceutical technology.
A comprehensive review of the current state of the art on various
computer aided applications in pharmaceutical technologyCase
studies are presented in order to facilitate understanding of
various concepts in computer-aided applications
Computer-Aided Applications in Pharmaceutical Technology: Delivery
Systems, Dosage Forms, and Pharmaceutical Unit Operations, Second
Edition covers the fundamentals of experimental design application
and interpretation in pharmaceutical technology, chemometric
methods with an emphasis on their applications in process control,
neural computing, data science, computer-aided biopharmaceutical
characterization, as well as the application of computational fluid
dynamics in pharmaceutical technology. Completely updated, the book
introduces the theory and practice of computational tools through
new case studies. Chapters cover Quality by Design in
pharmaceutical development, overview data mining methodologies,
present computer-aided formulation development, cover experimental
design applications, and much more.
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