Mycotoxins continue to be a very serious threat to human health and a major concern for those entrusted with regulatingthesafetyoffoodandfoodproducts.Infectionofcerealsandothercrops, notablegrapevine, byFusarium, Aspergillus andPenicillium are a world-wide problem and recent epidemics in Europe, the USA and Canada have focused attention on this problem. A previous Special Issue of the European Journal of Plant Pathology (108 (7) 2003) was concerned with the nature of these toxins and the fungi that can produce them. The aim of this publication is to review the environmental factors that in?uence the success of these fungi as pathogens and as organisms affecting stored products, and to discuss how these factors can also in?uence the amounts of toxin that accumulate. These reviews were originally presented at a Workshop of the EU COST Action 835 entitled 'Agriculturally Important Toxigenic Fungi' (Chairperson Antonio Logrieco, Bari, Italy), held in East Malling, UK at the Horticultural Research International in September 2002. We hope the information provided will stimulate scientists world-wide to assess the risk of toxins accumulating in plants under a range of environmental conditions and that this will provide an insight into how the accumulation of these toxins can be kept to a minimum. XiangmingXu JohnBailey MichaelCooke EuropeanJournalofPlantPathology109: 645-667, 2003. (c) 2003KluwerAcademicPublishers.

There is an urgent need to expand our knowledge of both the nature of the toxigenic fungi that are widespread on economically-important plants and the effect of their toxic secondary metabolites on human health. Informa tion about the production of mycotoxins by plant pathogens, particularly by species of Fusarium, Aspergillus and Penicillium, their occurrence in infected plants, as well as their role in the plant-pathogen interaction, for example as virulence/pathogenicity factors, is a pre-requisite for preventing plant disease and hence for reducing the Ievels of mycotoxin contamination. Fusarium infections in cereals and other crops are a particular problern world-wide and recent epidemics on wheat in Europe, the USA and Canada have again focused attention on this problem. Fur thermore, species ofAspergillus and Penicillium and their related mycotoxins, particularly Ochratoxin A, represent another consistent problern on cereals and grapes, especially in Europe where 40% of the global grape crop is grown. The aim of this publication is to gather together specialist updated reviews based on papers originally presented during a Workshop of EU Cost Action 835 entitled 'Agriculturally Important Taxigenie Fungi', held in Rome, 7-8 October 1999 at the Plant Pathology Research Institute. We hope the diversity of the contents will stimulate discussion, encourage the sharing of information and result in cross-fertilization of ideas needed for the solution of the present problems. This special issue will be of particular value to interdisciplinary scientists and especially mycologists, mycotoxicologists, plant pathologists and those concerned about the quality of food and food products.

This book is a collection of papers presented at a NATO Advanced Research Workshop on "Biology and Molecular Biology of Plant-Pathogen Interactions" which was held at Dillington College, Ilminster, UK, 1-6 September 1985. It had been preceded by Advanced Study Institutes at Porte Conte, Sardinia in 1975 and at Cape Sounion, Greece in 1981. In recent years, methods for the manipulation and transfer of genes have revolutionized our understanding of gene structure and function. It was thus opportune to bring together scientists from distinct disciplines, e. g. plant pathology, cytology, biochemistry and molecular biology to discuss our present understanding of cellular interactions between plants. We also explored how the potential offered by the newer molecular technologies could best be realized. It soon became evident at the Workshop, and is a repeated theme of this publication, that future research will need concentrated multi disciplinary programmes. Many of the new approaches will be valuable. For example, immunocytochemistry does, for the first time, allow molecules to be located precisely within infected tissues. Equally, the methods of DNA isolation and gene transformation will facilitate the isolation and characterization of genes associated with pathogenesis and specificity. The description at the Workshop of immunocytochemical protocols and of transformation systems for pathogenic fungi have already stimulated an upsurge in research on plant-pathogen relationships. The papers discuss many interactions between plants and fungal and bacterial pathogens, but also provide a comparison with mycorrhizal and symbiotic relationships, and those involving mycoparasites."

Mycotoxins continue to be a very serious threat to human health and a major concern for those entrusted with regulatingthesafetyoffoodandfoodproducts.Infectionofcerealsandothercrops, notablegrapevine, byFusarium, Aspergillus andPenicillium are a world-wide problem and recent epidemics in Europe, the USA and Canada have focused attention on this problem. A previous Special Issue of the European Journal of Plant Pathology (108 (7) 2003) was concerned with the nature of these toxins and the fungi that can produce them. The aim of this publication is to review the environmental factors that in?uence the success of these fungi as pathogens and as organisms affecting stored products, and to discuss how these factors can also in?uence the amounts of toxin that accumulate. These reviews were originally presented at a Workshop of the EU COST Action 835 entitled 'Agriculturally Important Toxigenic Fungi' (Chairperson Antonio Logrieco, Bari, Italy), held in East Malling, UK at the Horticultural Research International in September 2002. We hope the information provided will stimulate scientists world-wide to assess the risk of toxins accumulating in plants under a range of environmental conditions and that this will provide an insight into how the accumulation of these toxins can be kept to a minimum. XiangmingXu JohnBailey MichaelCooke EuropeanJournalofPlantPathology109: 645-667, 2003. (c) 2003KluwerAcademicPublishers.