In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, and speech disorders, as well as disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder.

How Genes Influence Behavior takes a personal and lively approach to the study of behavioral genetics, providing an up-to-date and accessible introduction to a variety of approaches and their application to a wide range of disorders, and modeling a critical approach to both methods and results. This second edition includes additional biology content to help students understand the biological foundations of the field, while maintaining an appropriate focus on the main issues of relevance to psychology students; updates coverage of genomic technologies and their applications; and covers a wider range of disorders, including autism spectrum disorder, eating disorders, and intellectual disability. A new final chapter guides students through a range of quantitative approaches using worked examples that relate directly to cases and examples used earlier in the text, and addresses current issues arising from debates around reproducibility. The online resources that accompany this book include: For students * Multiple choice questions for students to check their threshold knowledge * Data sets for students to manipulate, so that they can apply what they have learned For lecturers * Figures and tables from the book, ready to download

In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, and speech disorders, as well as disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder.