This book constitutes refereed proceedings of the 10th Ecuadorian Conference on Information and Communication Technologies, TICEC 2022, held in Manta, Ecuador, in October 2022. The 20 full papers were carefully reviewed and selected from 150 qualified submissions. The papers cover a great variety of topics, such as wireless communication, immersive environments, artificial intelligence, data mining, neural networks, augmented reality, cyberphysical systems, telemedicine, cybersecurity, software architecture, data processing, software development, and others. The contributions are divided into the following thematic blocks: ICTs Applications; Data Science; Software Development.