This book constitutes the proceedings of the 14th International Symposium on NASA Formal Methods, NFM 2022, held in Pasadena, USA, during May 24-27, 2022. The 33 full and 6 short papers presented in this volume were carefully reviewed and selected from 118submissions. The volume also contains 6 invited papers. The papers deal with advances in formal methods, formal methods techniques, and formal methods in practice. The focus on topics such as interactive and automated theorem proving; SMT and SAT solving; model checking; use of machine learning and probabilistic reasoning in formal methods; formal methods and graphical modeling languages such as SysML or UML; usability of formal method tools and application in industry, etc.