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Rapid progress in molecular biology, genetic engineering, and basic
research in immunology has opened up new possibilities for
application to diagnostic procedures and to clinical research. In a
short period a new era of diagnosis dawned, covering nearly all
fields of microbiology, immunology, and food technology. In
consequence of this rapid development, scientists of many
disciplines are involved studying infections of humans, animals,
and plants or working in technical microbiology. The application of
the newest findings of basic research to diagnostic work and to
clinical research covers nearly all fields of microbiology and
immunology. Moreover, it underlines the close relationship between
diagnosis, therapy, and epidemiology. An outstanding example of
these connections is given by the recent development of hepatitis B
vaccine. The discovery and identification of a non cultivable agent
by physicochemical and immunological methods were the heralds of a
new era in the prevention of infectious diseases. This book
provides an up-to-date, comprehensive review of developments and
future aspects in various fields. I am convinced that the authors
have succeeded in furnishing a large variety of new ideas and
possibilities. K.-O. HABERMEHL Contents Time Realities in the
Evaluation of Vaccines for Safety and Efficacy The Evaluation of
Vaccines M. R. HILLEMAN . . . . ."
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