This book constitutes the refereed proceedings of the Fourth Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, UNSURE 2022, held in conjunction with MICCAI 2022. The conference was hybrid event held from Singapore. For this workshop, 13 papers from 22 submissions were accepted for publication. They focus on developing awareness and encouraging research in the field of uncertainty modelling to enable safe implementation of machine learning tools in the clinical world.

This book constitutes the refereed proceedings of the Third International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, UNSURE 2021, and the 6th International Workshop on Preterm, Perinatal and Paediatric Image Analysis, PIPPI 2021, held in conjunction with MICCAI 2021. The conference was planned to take place in Strasbourg, France, but was held virtually due to the COVID-19 pandemic.For UNSURE 2021, 13 papers from 18 submissions were accepted for publication. They focus on developing awareness and encouraging research in the field of uncertainty modelling to enable safe implementation of machine learning tools in the clinical world. PIPPI 2021 accepted 14 papers from the 18 submissions received. The workshop aims to bring together methods and experience from researchers and authors working on these younger cohorts and provides a forum for the open discussion of advanced image analysis approaches focused on the analysis of growth and development in the fetal, infant and paediatric period.

This book constitutes the refereed proceedings of the Second International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, UNSURE 2020, and the Third International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020. The workshops were held virtually due to the COVID-19 pandemic.For UNSURE 2020, 10 papers from 18 submissions were accepted for publication. They focus on developing awareness and encouraging research in the field of uncertainty modelling to enable safe implementation of machine learning tools in the clinical world. GRAIL 2020 accepted 10 papers from the 12 submissions received. The workshop aims to bring together scientists that use and develop graph-based models for the analysis of biomedical images and to encourage the exploration of graph-based models for difficult clinical problems within a variety of biomedical imaging contexts.