Metabolites as signals in immunity and inflammation describes the revolution in the definition of the word metabolism. It highlights changes in thinking about the whole field of immunology. These changes occur thanks to breakthrough experiments in basic research with the help of new technologies allowing to test immunology hypotheses.In recent years a substantial number of findings have been made around immunometabolism, by which the changes in intracellular metabolic pathways in immune cells that alter their function are meant. What is emerging is a complex interplay between metabolic reprogramming and immunity, which is providing an extra dimension to our understanding of the immune system in health and diseaseAfter reading this book readers will realize countless opportunities in altering cell fate leading to outcome of diseases by altering metabolic pathways. Metabolites as signals in immunity and inflammation is a must for those wanting to dive into this novel field of iimmunometabolism.

Science is a serious business, right? Wrong. Scientists have been participants in the best reality show of all time, with all the highs, lows, bust-ups, and strange personalities of any show on telly today. This hugely accessible history of science reveals the human stories behind the biggest discoveries. For example, we meet Charles Darwin as he weighs up the pros and cons of marrying his cousin: 'constant companion' vs 'less money for books'. Tough call. To Boldly Go Where No Book Has Gone Before covers everything from space travel and evolution to alchemy and AI. Written by one of our leading scientists, this is an insider's account that celebrates the joy of science. It is filled with all the juicy bits that other histories leave out.

Taking us on an incredible journey across centuries and galaxies, accompanied by his characteristic wit, Professor Luke O'Neill explains how it all began, how it all will end and everything in between. Readers will benefit from Luke's insatiable curiosity for life when they dive into this ultimate journey through life and death. Among many fascinating facts, you'll discover the science behind how we got to be so smart, why sex with a caveman was a good idea, the science of finding love, why we follow religions, and how robots will become part of everyday life. Humanology is a humbling reminder that we're just a small speck in a big universe - so sit back and embrace the adventure. 'A man who can explain 4.2 billion years of life on Earth and make me laugh at the same time - sheer genius.' Pat Kenny, Newstalk

Join Trinity's Professor Luke O'Neill on the greatest journey of them all. From the very big to the very small - vast galaxies to microscopic atoms - travel through the wonders of the universe, the mysteries of the human body, and the tiny world of molecules. Discover the Irish scientists that have helped to shape our world and find out how to become one yourself. How do we measure the universe? Why do we need plants? How do our bodies repair themselves when we are ill? What species will exist on earth in a million years' time? Discover the answers to these questions and a lot more in this thrilling and engrossing book packed with fascinating phenomena, vibrant illustrations, experiments you can do yourself, and heaps of fun facts.

What makes us human? Ireland's favourite scientist is here to tell you! What do you have in common with the 7.75 billion other people on the planet? This is the question that Professor Luke O'Neill attempts to answer in this exciting new book for young readers, adapted from his bestselling book for adults, Humanology: A Scientist's Guide to our Amazing Existence. Starting with the origin of life and how we as a species evolved on the plains of Africa some 200,000 years ago, Professor Luke explores what makes us interesting as a species, why we sleep, laugh and enjoy music, and our efforts to stop disease. He also ponders whether we will create superhumans, how and why we age, if we can escape death and whether our eventual extinction is inevitable. With Luke's trademark infectious enthusiasm - and plenty of laughs along the way - What Makes Us Human is the perfect book for curious minds.

Never Mind the B#ll*cks, Here’s the Science is Professor Luke O’Neill’s biggest runaway bestseller in which he grapples with life's biggest questions and tells us what science has to say about them. Now adapted for children, Show Me the Science asks the same questions – do we have control over our lives? can we escape working in terrible jobs? why do we need vaccinations? are men’s and women's brains different? will we destroy the planet? – and encourages children to apply a scientific mindset in attempting to answer them.   Covering topics from global pandemics to artificial intelligence, this is a celebration of science and all the brilliant answers it can offer us for a budding generation of professors!

A number one Irish bestseller, and winner of the Popular Non-Fiction Book of the Year at the Irish Book Awards In this fascinating and thought-provoking book, Professor Luke O'Neill grapples with life's biggest questions and tells us what science has to say about them. Covering topics from global pandemics to gender, addiction to euthanasia, Luke O'Neill's easy wit and clever pop-culture references deconstruct the science to make complex questions accessible. Arriving at science's definitive answers to some of the most controversial topics human beings have to grapple with, Never Mind the B#ll*ocks, Here's the Science is a celebration of science and hard facts in a time of fake news and sometimes unhelpful groupthink. 'A celebration of scientific fact in an era characterised by nebulous subjectivity' Irish Times

Take a front row seat with Professor Luke O'Neill on a high-octane year. Luke has become one of the most well-known and trusted voices of Ireland's COVID-19 pandemic. A world-renowned immunologist, he was thrust into the spotlight as we struggled to make sense of a crisis that saw the country grind to a halt. In these compelling diaries, Luke reveals what life was like behind the scenes as he endeavoured to keep calm and trust that the science would save us. Set against a national backdrop of banana-bread baking, TikTok dancing and outdoor bingo, as well as the devastation to life and livelihood suffered by many, Luke's lockdown diaries reveal the highs and lows of work at the cutting edge of science in his Trinity College lab along with how he coped personally with the pressures of public life. Shot through with the natural positivity and humour that have made Luke a home-grown hero, Keep Calm and Trust the Science is an unputdownable account of one of the most dramatic years in Irish history from one of its key players.