This book describes the whole field of endoprosthetics, with all its potential, for practicing clinicians. The following aspects are dealt with in particular: indications and contraindications, surgical procedures (pros and cons), pain therapy, post-operative problems, infections, risks, necessary medication, length of medication, and post-operative patient care.

Manfred Georg Krukemeyer first describes magnetic drug targeting, by which is meant the focused application of drugs, e.g. the introduction of a cytostatic, and which is aimed at optimising its locally therapeutic effect. The author thus achieves a high concentration of cytostatic at the site of the tumour. The particles have to be large enough to be attracted by a magnetic field and so find their way into the tumour, where they release their active ingredient. The aim of the hypothesis formed by one of the author's study groups was to show in a scientific experiment that in this case cytostatics coupled with iron particles [Fe3O4] can be introduced into a tumour. The focused introduction of drugs - magnetic drug targeting - results in faster arrival of the active ingredient at the target site together with a reduced quantity of active substances. For this reason magnetic drug targeting is also interesting from an economic point of view.

Die Transplantation gesunder Organe, Gewebe oder Zellen ist durch den Fortschritt der Hochleistungsmedizin zum etablierten Routineverfahren bei der Behandlung des irreversiblen Organversagens geworden. Das Thema Transplantationsmedizin ist an zukunftstrachtige und kontroverse Forschungsgebiete wie die der Stammzellenforschung und Immunbiologie gekoppelt. Dieses Werk wurde von prominenten Wissenschaftlern aus den jeweiligen Gebieten der Transplantationsmedizin geschrieben. Es soll dem niedergelassenen Arzt alle Aspekte der Transplantationsmedizin und ihren Nutzen fur den Patienten nahe bringen. Kurze, ubersichtliche Kapitel zu theoretischen Grundlagen - uber rechtliche, ethische bis hin zu philosophischen Fragestellungen - sowie Kapitel, die alle wichtigen Organe und Organgruppen behandeln und auf das komplexe Gebiet der Immunreaktionen eingehen, beantworten dem Arzt alle Fragen zur Transplantation. Besonderer Wert wird auf Rehabilitation gelegt. Eine Marginalspalte foerdert eine schnelle Orientierung.

Each year in Germany, some 200,000 people undergo hip replacement surgery. Clear and concisely written, this book provides a comprehensive discussion of endoprosthetics and its future. Special attention is devoted to indications and contraindications, different surgical procedures (pro and contra), pain therapy, costs, postoperative complications, infections, risks, medications, length of treatment, and postoperative patient care. In order to help with treatment and care decisions, the book conveys specialized knowledge with a strong practical emphasis (e.g. by including information on hip implant manufacturers, price and quality comparisons, and multicolor illustrations). A special layout and color-coded margin assist quick reference.

Manfred Georg Krukemeyer beschreibt zunachst das Magnetic Drug Targeting, unter dem man die zielgerichtete Arzneimittelapplikation - z. B. das Schleusen eines Zytostatikums - versteht und das eine Optimierung des lokaltherapeutischen Effekts erreichen soll. So erreicht der Autor am Ort des Tumors eine hohe Konzentration des Zytostatikums. Die Partikeln mussen gross genug sein, um von einem Magnetfeld angezogen zu werden, und wandern so in den Tumor, um dort ihren Wirkstoff freizusetzen. Ziel der Hypothese einer Studiengruppe des Autors war es, in einem wissenschaftlichen Experiment darzulegen, dass in diesem Fall Zytostatika an Eisenpartikeln gekoppelt [Fe3O4], in einen Tumor geschleust werden koennen. Das zielgerichtete Schleusen von Medikamenten - Magnetic Drug Targeting - fuhrt zu einem schnelleren Erreichen des Wirkstoffs am Zielort bei einer verminderten Menge an Wirksubstanzen. Von daher ist das Magnetic Drug Targeting auch unter oekonomischen Aspekten interessant.

Medical education is a life-long process, and it is important for beginning medical students to gain a solid understanding of the basics within the first year of medical school. Introductory Guide to Medical Training: From Basic Sciences to Medical Specialties is a concise yet thorough overview of the medical field that will prepare first-year students for their educational journey and provide laypersons with a glimpse into the particularities of the medical specialties. The book begins with the fundamentals and culture of medicine, tips and tricks for learning and retaining medical knowledge, and a summary of how the medical field has evolved through time. The second half of the book features sections on several major specialties, including: anatomy, physiology, biochemistry, pharmacology, neurology, pediatrics, men's and women's health, forensic pathology, and surgery, among many others. Highlights: Full-color, high-quality charts, graphs, and tables that showcase global statistics and supplement the material presented in the text Short, succinct biographies of major figures who have helped shape modern medicine A list of commonly used abbreviations encountered in medicine This book is the perfect exploratory text for laypersons and all those considering or pursuing a medical degree, and it will ensure that they are well prepared for the challenges that lie ahead of them.