This book covers classic epidemiological designs that use a reference/control group, including case-control, case-cohort, nested case-control and variations of these designs, such as stratified and two-stage designs. It presents a unified view of these sampling designs as representations of an underlying cohort or target population of interest. This enables various extended designs to be introduced and analysed with a similar approach: extreme sampling on the outcome (extreme case-control design) or on the exposure (exposure-enriched, exposure-density, countermatched), designs that re-use prior controls and augmentation sampling designs. Further extensions exploit aggregate data for efficient cluster sampling, accommodate time-varying exposures and combine matched and unmatched controls. Self-controlled designs, including case-crossover, self-controlled case series and exposure-crossover, are also presented. The test-negative design for vaccine studies and the use of negative controls for bias assessment are introduced and discussed. This book is intended for graduate students in biostatistics, epidemiology and related disciplines, or for health researchers and data analysts interested in extending their knowledge of study design and data analysis skills. This book Bridges the gap between epidemiology and the more mathematically oriented biostatistics books. Assembles the wealth of epidemiological knowledge about observational study designs that is scattered over several decades of scientific publications. Illustrates the performance of methods in real research applications. Provides guidelines for implementation in standard software packages (Stata, R). Includes numerous exercises, covering simple mathematical proofs, consideration of proposed or published designs, and practical data analysis.

What is the nature of power in Racinian tragedy? Few questions have generated such widespread critical disagreement. This study looks beyond the conventional pageant of political power in the plays by exploring tensions inherent in the very concept of power. Each chapter elucidates how Racine's power relationships are concentrated in the question of language. His characters seek to discover, channel and control the thoughts of others by means of a careful manipulation of the word. The limits of language and the way it can be distorted and controlled rather than its expressiveness are shown to be crucial to Racine's power struggles. This book examines Racine's portrayal of the disintegration of the processes of thought by means of linguistic engineering, showing how it mirrors the absolutist policies of Louis XIV and foreshadows more recent anxieties about the use and abuse of language in our own time. It therefore provides a new reading of Racine's use of language which challenges previous critical responses. The emphasis throughout is on close engagement with the text.

IT'S BETTER THAN A BOOK CLUB

Have More Fun, Live More Wholeheartedly, Encourage Each Other

This "how -to" manual covers everything you need to know to successfully create your own Creativity & Camaraderie Club. The clear, detailed structure was created by two psychotherapists with decades of experience knowing "what works" to help your group thrive and survive.

A Creativity & Camaraderie Club gives you permission to quench your thirst for creative expression and play.

It feeds your hunger for meaningful community as you pursue old passions or explore new ones. You will expand your definition of " creativity" into many arenas of wholehearted living.

You are a great candidate for a Creativity & Camaraderie Club if you:

want to have more fun...just because you feel like it

want to re-new your wholehearted engagement in life

desire to open your heart to new community connections

are one of the "creatively wounded" who thinks "I'm not creative," "I have no imagination" (just glance at Appendix B to see what "non-artists" have done as a result of monthly meetings )

are an "already creative" - a writer, painter, dancer, knitter, potter, entrepreneur, etc. who wants more structured accountability to keep creating

WILL YOU GIVE YOURSELF THE GIFT OF ENLIVENING COMMUNITY?

""How could you resist bringing more joy and fun into your life?"" (Dale Schwarz, M. Ed., ATR, LMHC Center for Creative Consciousness)

""Just thinking each month about what I can do creatively has transformed my life. Most importantly, I met fabulous women "" (Patricia O'Connor, Life Coach, ChFc)

""I love the support, energy, and enthusiasm of women sharing their lives and cheering one another on at our monthly creativity meetings. I love witnessing and being witnessed. Our creativity club has made my life fuller and given me a feeling of friendship and unconditional lovingness."" (Judy Wolf Writer & Life Adventurer)

" "I just LOVE my creativity group Creativity seems to be the "glue" or the focal point for unfolding who we are. It's a safe place to share whatever we create, think, feel."" ( Barb Trevvett, Retired LMFT}

""Our creativity club meeting on the second Wednesday of each month is a holy day of obligation for me It is built into my calendar. I feel like a thirst has been quenched. I begin to look forward to our meetings the very morning after we've just met. The network of women is an incredible gift of the highest good" " (Nancy Zumpano, High school Math teacher )

What is the nature of power in Racinian tragedy? Few questions have generated such widespread critical disagreement. This study looks beyond the conventional pageant of political power in the plays by exploring tensions inherent in the very concept of power. Each chapter elucidates how Racine's power relationships are concentrated in the question of language. His characters seek to discover, channel and control the thoughts of others by means of a careful manipulation of the word. The limits of language and the way it can be distorted and controlled rather than its expressiveness are shown to be crucial to Racine's power struggles. This book examines Racine's portrayal of the disintegration of the processes of thought by means of linguistic engineering, showing how it mirrors the absolutist policies of Louis XIV and foreshadows more recent anxieties about the use and abuse of language in our own time. It therefore provides a new reading of Racine's use of language which challenges previous critical responses. The emphasis throughout is on close engagement with the text.