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The 2002 Nobel Prize in Physiology or Medicine was awarded to
Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E.
Sulston (UK) "for their discoveries concerning genetic regulation
of organ development and programmed cell death." Cell death is a
fundamental aspect of embryonic development, normal cellular
turnover and maintenance of homeostasis (maintaining a stable,
constant environment) on the one hand, and aging and disease on the
other. This volume addresses the significant advances with the
techniques that are being used to analyze cell death.
* This volume provides the necessary, trusted methods to carry out
this research on the latest techniques. Once researchers understand
the molecular mechanisms of the apoptotic pathways, they can begin
to develop new therapies.
* Presents key methods on studying tumors and how these cancer
cells evade cell death.
* Eliminates searching through many different sources to avoid
pitfalls so the same mistakes are not made over and over.
One of the major goals of researchers in the field of apoptosis is
to identify targets for novel therapies in cancer, AIDS, and
Alzheimer s disease. Understanding the molecular mechanisms of the
various components of the apoptotic pathways is the first step to
reaching this goal.
The 2002 Nobel Prize in Physiology or Medicine was awarded to
Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E.
Sulston (UK) "for their discoveries concerning genetic regulation
of organ development and programmed cell death." Cell death is a
fundamental aspect of embryonic development, normal cellular
turnover and maintenance of homeostasis (maintaining a stable,
constant environment) on the one hand, and aging and disease on the
other. This volume addresses the significant advances with the
techniques that are being used to analyze cell death.
* This volume provides the necessary, trusted methods to carry out
this research on these latest therapeutic techniques. Once
researchers understand the molecular mechanisms of the apoptotic
pathways, they can begin to develop new therapies.
* Presents key methods on studying tumors and how these cancer
cells evade cell death.
* Eliminates searching through many different sources to avoid
pitfalls so the same mistakes are not made over and over."
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