This book explores central aspects of genetic modification of animals for scientific purposes in the context technological possibilities, regulatory issues in different regions, animal welfare implications and wider ethical issues, exemplified through current theories and frameworks. This discussion of lab animals produced through modern biotechnologies becomes increasingly pressing as CRISPR-Cas9 technology advances rapidly, challenging legal and ethical frameworks all over the world. Such animals are now affordable and readily available to almost every branch of scientific research. This raises enormous potential for creating ‘tailored’ models for human diseases but also rubs up against the traditional guiding principles (the 3Rs) for the humane use of animals for scientific experiments and raises wider ethical issues around death, integrity, and naturalness. In this book, expert authors from diverse backgrounds in laboratory animal care, animal research, technology and animal rights explore a range of topics, from the science behind biotech research animals and the regulation of their use, to utilitarian, animal rights, virtue ethics, and ethic of care perspectives on the use of these technologies. Whatever your background or role in animal research, this book will challenge and stimulate deeper consideration of the benefits, disadvantages, and ethical consequences of the use of biotechnology in the animal laboratory.

This book explores central aspects of genetic modification of animals for scientific purposes in the context technological possibilities, regulatory issues in different regions, animal welfare implications and wider ethical issues, exemplified through current theories and frameworks. This discussion of lab animals produced through modern biotechnologies becomes increasingly pressing as CRISPR-Cas9 technology advances rapidly, challenging legal and ethical frameworks all over the world. Such animals are now affordable and readily available to almost every branch of scientific research. This raises enormous potential for creating ‘tailored’ models for human diseases but also rubs up against the traditional guiding principles (the 3Rs) for the humane use of animals for scientific experiments and raises wider ethical issues around death, integrity, and naturalness. In this book, expert authors from diverse backgrounds in laboratory animal care, animal research, technology and animal rights explore a range of topics, from the science behind biotech research animals and the regulation of their use, to utilitarian, animal rights, virtue ethics, and ethic of care perspectives on the use of these technologies. Whatever your background or role in animal research, this book will challenge and stimulate deeper consideration of the benefits, disadvantages, and ethical consequences of the use of biotechnology in the animal laboratory.

The use of animals in research has always been surrounded by ethical controversy. This book provides an overview of the central ethical issues focusing on the interconnectedness of science, law and ethics. It aims to make theoretical ethical reasoning understandable to non-ethicists and provide tools to improve ethical decision making on animal research. It focuses on good scientific practice, the 3Rs (replacement, reduction and refinement), ethical theories applied to specific cases and an overview of regulatory issues. The book is co-authored by experts in animal research, animal welfare, social sciences, law and ethics, and provides both animal researchers and members of animal ethics committees with knowledge that can facilitate their work and communication with stakeholders and the public. The book is written to provide knowledge, not to argue a certain position, and is intended to be used in training that aims to fulfil EU Directive 2010/63/EU.

The use of animals in research has always been surrounded by ethical controversy. This book provides an overview of the central ethical issues focusing on the interconnectedness of science, law and ethics. It aims to make theoretical ethical reasoning understandable to non-ethicists and provide tools to improve ethical decision making on animal research. It focuses on good scientific practice, the 3Rs (replacement, reduction and refinement), ethical theories applied to specific cases and an overview of regulatory issues. The book is co-authored by experts in animal research, animal welfare, social sciences, law and ethics, and provides both animal researchers and members of animal ethics committees with knowledge that can facilitate their work and communication with stakeholders and the public. The book is written to provide knowledge, not to argue a certain position, and is intended to be used in training that aims to fulfil EU Directive 2010/63/EU.

The Good, the Right, and the Fair is a comprehensive introduction to contemporary moral and political philosophy especially suited for undergraduate students in medicine and the life sciences. The book covers first questions concerning the good: What makes a life worth living? Is it only humans who matter morally? Is welfare all that matters? It then proceeds to a discussion of the right: How ought we to act? The major ethical theories of the western tradition are presented and their strengths and weaknesses discussed. Finally, key aspects of the philosophical discussion of the fair, including matters of equality, justice, and liberty, are laid out for the reader. Emphasizing a pluralism of reasonable views, and with illustrative examples drawn primarily from medicine and the life sciences, this book is meant to spur interest in, and to qualify deliberation about ethical issues, rather than to advance specific conclusions concerning morality and justice.