Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

This poignant coming-of-age story will change your perception of what shonen manga can be.
Reads R to L (Japanese Style), for audiences T
With Ko in his second year of high school and Aoba in her first, the regionals for Summer Koshien are about to begin The third round pits Seishu up against mighty Ryuou Gakuin--one of the teams favored to win the whole shebang. Do Ko and team have what it takes to even advance that far in the tourney? But first, Aoba's cousin enters the picture, and he might shake things up on a different front.

This poignant coming-of-age story will change your perception of what shonen manga can be.
Reads R to L (Japanese Style).
In the summer of his second year in high school, Ko and the Seishu baseball team must take on mighty Ryuou Gakuin and their genius slugger Keitaro Mishima. With everything on the line, will destiny find Seishu moving on to the next round? Later, new neighbors are setting up shop next to Kitamura Sports, and their daughter bears a striking resemblance to Wakaba...

Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.