This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.

This book discusses advancements in the applications of nanoparticles in tissue engineering. It examines the applications of nanobiomaterials in hard tissue regeneration, fabrication, and characterization. The book also analyzes the implication of three-dimensional and four-dimensional fabrication techniques for the production of the scaffold in tissue engineering and their advantages over conventional scaffold production techniques. Further, it presents smart materials used in making 4-D scaffolds that imitate the dynamic response of tissue against natural stimuli and adapt to the microenvironment by changing their conformation or other properties. It also summarizes the growing field of biomolecular detection and biosensors in tissue engineering and the increasing prominence of nanoparticles in the biosensors. Further, it provides the future outlook and associated challenges of the application of nanomaterials in tissue engineering.

This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.

This book discusses the current state of knowledge about potential drug targets against malaria. It reviews the current drug targets and focuses on the progress made on the latest scientific and technological advances in discovering and developing novel antimalarial agents. The initial chapter discusses the existing antimalarial agent, including quinoline derivatives, an antifolate, and artemisinin derivatives. It further explores the potential of Plasmodium kinases as drug targets for the treatment of malaria. Notable, the book examines the major metabolic pathways of the parasite that are explored as novel sites for drug design, including heme detoxification, fatty acid synthesis, nucleic acid synthesis, fatty acid synthesis, and oxidative stress. This volume also presents antineoplastic chemotherapy that targets DNA replication and other cancer agents against the malaria parasites with possible off-target action. Lastly, it discusses Plasmodium proteases, a suitable multistage target for designing novel drugs with new modes of action to combat malaria. ​