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Many diseases earlier considered to be incurable are now being
treated with modern innovations involving fetal tissue transplants
and stem cells derived from fetal tissues. Fetal tissues are the
richest source of fetal stem cells as well as other varying states
of differentiated cells and support or stromal cells. The activity
of such stem cells is at their peak provided they are given the
correct niche. Stem cells, as we know, are immortal cells with the
capacity to regenerate into any kind of differentiated cell as per
niche-guidance. As such, fetal tissues have the potential capacity
to mend, regenerate and repair damaged cells or tissues in adults,
when directly transplanted to the site of injury, or even when
transplanted in some other site, because it may have a homing
capacity to migrate to the site of the specific injured organ. This
is a new area of translational research and needs to be highlighted
because of its immense potential. This book will bring together the
new work of prominent medical scientists and clinicians who are
conducting pioneering research in human fetal tissue
transplantation. This will include direct transplant of healthy
fetal tissue into mature patients as well as in hosts with genetic
diseases. Transplant techniques, donor-host interaction, cell and
tissue storage, ethical and legal issues, are some of the many
matters which the book will deal with.
This book represents a major contribution to the emerging science
of regenerative medicine using non-fetal sources of stem cells. The
Editors, Dr Niranjan Bhattacharya and Professor Phillip
Stubblefield, have brought together some of the most pre-eminent
scientists working on regenerative medicine to share information on
currently ongoing work in this area alongside unpublished
observations that will help to shape the contours of future
therapies. Regenerative Medicine: Using Non-Fetal Sources of Stem
Cells discusses the potential clinical and therapeutic applications
using non-fetal stem cells as well as providing instruction on the
collection, isolation and characterization of stem cells from
various non-fetal sources, such as menstrual blood, adipose tissue,
breast milk and uprooted decidual teeth. This book will be an
invaluable resource for both active researches and those entering
the field. The Editors truly hope that the text will act as a
stimulant to professionals and clinical scientists, who may be
inspired to further the work of the pioneering scientists who have
contributed to this volume.
Many diseases earlier considered to be incurable are now being
treated with modern innovations involving fetal tissue transplants
and stem cells derived from fetal tissues. Fetal tissues are the
richest source of fetal stem cells as well as other varying states
of differentiated cells and support or stromal cells. The activity
of such stem cells is at their peak provided they are given the
correct niche. Stem cells, as we know, are immortal cells with the
capacity to regenerate into any kind of differentiated cell as per
niche-guidance. As such, fetal tissues have the potential capacity
to mend, regenerate and repair damaged cells or tissues in adults,
when directly transplanted to the site of injury, or even when
transplanted in some other site, because it may have a homing
capacity to migrate to the site of the specific injured organ. This
is a new area of translational research and needs to be highlighted
because of its immense potential. This book will bring together the
new work of prominent medical scientists and clinicians who are
conducting pioneering research in human fetal tissue
transplantation. This will include direct transplant of healthy
fetal tissue into mature patients as well as in hosts with genetic
diseases. Transplant techniques, donor-host interaction, cell and
tissue storage, ethical and legal issues, are some of the many
matters which the book will deal with.
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